Evidence map›Paper›PMID 29354214›Full record

ArticleDementia & neuropsychologia

A panel of clinical and neuropathological features of cerebrovascular disease through the novel neuroimaging methods.

Gilberto Sousa Alves, Luiza de Amorim de Carvalho, Felipe Kenji Sudo, Lucas Briand, Jerson Laks, Eliasz Engelhardt

Open access · diamondAbstract read
In one paragraph

Article in Dementia & neuropsychologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Gilberto Sousa AlvesDepartamento de Medicina Interna, Universidade Federal do Ceará, CE, Brazil.
Luiza de Amorim de CarvalhoDepartamento de Medicina Interna, Universidade Federal do Ceará, CE, Brazil.
Felipe Kenji SudoDepartamento de Psicologia, Pontifícia Universidade Católica do Rio de Janeiro, RJ, Brazil.
Lucas BriandDepartamento de Medicina Interna, Universidade Federal do Ceará, CE, Brazil.
Jerson LaksInstituto de Psiquiatria, Universidade Federal do Rio de Janeiro, RJ, Brazil.
Eliasz EngelhardtSetor de Neurologia Cognitiva e do Comportamento, Instituto de Neurologia Deolindo Couto (INDC-CDA/IPUB), Rio de Janeiro, RJ, Brazil.
Universidade Federal do Ceará · BRPontifical Catholic University of Rio de Janeiro · BRUniversidade Unigranrio · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The last decade has witnessed substantial progress in acquiring diagnostic biomarkers for the diagnostic workup of cerebrovascular disease (CVD). Advanced neuroimaging methods not only provide a strategic contribution for the differential diagnosis of vascular dementia (VaD) and vascular cognitive impairment (VCI), but also help elucidate the pathophysiological mechanisms ultimately leading to small vessel disease (SVD) throughout its course.

objectiveIn this review, the novel imaging methods, both structural and metabolic, were summarized and their impact on the diagnostic workup of age-related CVD was analysed. Methods: An electronic search between January 2010 and 2017 was carried out on PubMed/MEDLINE, Institute for Scientific Information Web of Knowledge and EMBASE.

resultsThe use of full functional multimodality in simultaneous Magnetic Resonance (MR)/Positron emission tomography (PET) may potentially improve the clinical characterization of VCI-VaD; for structural imaging, MRI at 3.0 T enables higher-resolution scanning with greater imaging matrices, thinner slices and more detail on the anatomical structure of vascular lesions.

conclusionAlthough the importance of most of these techniques in the clinical setting has yet to be recognized, there is great expectancy in achieving earlier and more refined therapeutic interventions for the effective management of VCI-VaD.

Indexed as

diffusion tensor imagingDTIMRIneuroimagingnovel methodsPETvascular

Identifiers

PMID29354214
PMCPMC5769992
OpenAlexW2782651618

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.