Evidence map›Paper›PMID 29354131›Full record

ArticleFrontiers in immunology2017

Dynamics of CD4 and CD8 T-Cell Subsets and Inflammatory Biomarkers during Early and Chronic HIV Infection in Mozambican Adults.

Lucía Pastor, Victor Urrea, Jorge Carrillo, Erica Parker, Laura Fuente-Soro, Chenjerai Jairoce, Inacio Mandomando, Denise Naniche, Julià Blanco

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 31 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Review
  5. Article
  6. Under the Radar: Immune Evasion, Pathogenesis and Control of HIV Infection.International journal of molecular sciences · 2025
    Review
  7. Article
  8. Youden index estimation based on group-tested data.Statistical methods in medical research · 2025
    Article
  9. Article
  10. The role of immune activation and antigen persistence in acute and long COVID.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2023
    Review
  11. Article
  12. Article
  13. Article
  14. Association between CD4BMC infectious diseases · 2021
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Expansion of Stem Cell-Like CD4Journal of virology · 2019
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Lucía PastorAIDS Research Institute-IrsiCaixa, Hospital Germans Trias i Pujol, Badalona, Spain.
Victor UrreaAIDS Research Institute-IrsiCaixa, Hospital Germans Trias i Pujol, Badalona, Spain.
Jorge CarrilloAIDS Research Institute-IrsiCaixa, Hospital Germans Trias i Pujol, Badalona, Spain.
Erica ParkerSchool of Paediatrics and Child Health, University of Western Australia, Perth, WA, Australia.
Laura Fuente-SoroISGlobal, Barcelona Centre for International Health Research (CRESIB), Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Chenjerai JairoceCentro de Investigação em Saúde da Manhiça (CISM), Maputo, Mozambique.
Inacio MandomandoCentro de Investigação em Saúde da Manhiça (CISM), Maputo, Mozambique.
Denise NanicheISGlobal, Barcelona Centre for International Health Research (CRESIB), Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Julià BlancoAIDS Research Institute-IrsiCaixa, Hospital Germans Trias i Pujol, Badalona, Spain.
Manhiça Health Research Centre · MZBarcelona Institute for Global Health · ESHospital Universitari Germans Trias i Pujol · ESIrsiCaixa · ESUniversity of Western Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During primary HIV infection (PHI), there is a striking cascade response of inflammatory cytokines and many cells of the immune system show altered frequencies and signs of extensive activation. These changes have been shown to have a relevant role in predicting disease progression; however, the challenges of identifying PHI have resulted in a lack of critical information about the dynamics of early pathogenic events. We studied soluble inflammatory biomarkers and changes in T-cell subsets in individuals at PHI (

Indexed as

acute HIV infectionAIDScytokinesHIV pathogenesisimmunosenescencesub-Saharan AfricaT-cell activationT-cell exhaustion

Identifiers

PMID29354131
PMCPMC5760549
OpenAlexW2782136952

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.