Evidence map›Paper›PMID 29354014›Full record

ArticleKorean journal of radiology

Efficacy and Safety of Radiofrequency Ablation for Benign Thyroid Nodules: A Prospective Multicenter Study.

So Lyung Jung, Jung Hwan Baek, Jeong Hyun Lee, Young Kee Shong, Jin Yong Sung, Kyu Sun Kim, Ducky Lee, Ji-Hoon Kim, Seon Mi Baek, Jung Suk Sim and 1 more

Open access · hybridAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Korean journal of radiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed, 11 pooled it
17.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 11 syntheses or guidelines pooled it, 204 citations in OpenAlex.

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25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

So Lyung JungDepartment of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Jung Hwan BaekDepartment of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul 05505, Korea.
Jeong Hyun LeeDepartment of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul 05505, Korea.
Young Kee ShongDepartment of Endocrinology and Metabolism, University of Ulsan College of Medicine, Asan Medical Center, Seoul 05505, Korea.
Jin Yong SungDepartment of Radiology, Thyroid Center, Daerim St. Mary's Hospital, Seoul 07442, Korea.
Kyu Sun KimDepartment of Radiology, Thyroid Center, Daerim St. Mary's Hospital, Seoul 07442, Korea.
Ducky LeeDepartment of Internal Medicine, Thyroid Center, Daerim St. Mary's Hospital, Seoul 07442, Korea.
Ji-Hoon KimDepartment of Radiology, Seoul National University College of Medicine, Seoul 03080, Korea.
Seon Mi BaekDepartment of Radiology, Sharing and Happiness Hospital, Busan 48101, Korea.
Jung Suk SimDepartment of Radiology, Withsim Clinic, Seongnam 13590, Korea.
Dong Gyu NaDepartment of Radiology, Human Medical Imaging & Intervention Center, Seoul 06524, Korea.
Seoul St. Mary's Hospital · KRAsan Medical Center · KRSeoul Medical Center · KRSeoul National University · KRUniversity of Ulsan · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To assess the efficacy and safety of thyroid radiofrequency (RF) ablation for benign thyroid nodules by trained radiologists according to a unified protocol in a multi-center study. Materials and Methods: From 2010 to 2011, 345 nodules from 345 patients (M:F = 43:302; mean age ± SD = 46.0 ± 12.7 years, range = 15-79) who met eligibility criteria were enrolled from five institutions. At pre-ablation, the mean volume was 14.2 ± 13.2 mL (1.1-80.8 mL). For 12 months or longer after treatment, 276 lesions, consisting of 248 solid and 28 predominantly cystic nodules, were followed. All operators performed RF ablation with a cool-tip RF system and two standard techniques (a transisthmic approach and the moving-shot technique). Volume reduction at 12 months after RF ablation (the primary outcome), therapeutic success, improvement of symptoms as well as of cosmetic problems, and complications were evaluated. Multiple linear regression analysis was applied to identify factors that were independently predictive of volume reduction. Results: The mean volume reduction at 12 months was 80.3% (n = 276) and at the 24-, 36-, 48-, and 60-month follow-ups 84.3% (n = 198), 89.2% (n = 128), 91.9% (n = 57), and 95.3% (n = 6), respectively. Our therapeutic success was 97.8%. Both mean symptom and cosmetic scores showed significant improvements ( Conclusion: Radiofrequency ablation performed by trained radiologists from multiple institutions using a unified protocol and similar devices was effective and safe for treating benign thyroid nodules.

Indexed as

Catheter AblationAdolescentAdultAgedFemaleFollow-Up StudiesHumansLinear ModelsMaleMiddle AgedProspective StudiesThyroid NeoplasmsThyroid NoduleTreatment OutcomeYoung AdultInterventionNeoplasmNoduleProspective studyRadiofrequency ablationThyroidTumorUltrasound

Identifiers

PMID29354014
PMCPMC5768499
OpenAlexW2776420589

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.