Evidence map›Paper›PMID 29354009›Full record

ArticleKorean journal of radiology

Assessing the Blood Supply Status of the Focal Ground-Glass Opacity in Lungs Using Spectral Computed Tomography.

Guanfu Liu, Mengying Li, Guosheng Li, Zhiyong Li, Ailian Liu, Renwang Pu, Huizhi Cao, Yijun Liu

Open access · hybridAbstract read
In one paragraph

Article in Korean journal of radiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Guanfu LiuDepartment of Radiology, First Affiliated Hospital of Dalian Medical University, Liaoning 116011, China.
Mengying LiDepartment of Radiology, First Affiliated Hospital of Dalian Medical University, Liaoning 116011, China.
Guosheng LiDepartment of Radiology, First Affiliated Hospital of Dalian Medical University, Liaoning 116011, China.
Zhiyong LiDepartment of Radiology, First Affiliated Hospital of Dalian Medical University, Liaoning 116011, China.
Ailian LiuDepartment of Radiology, First Affiliated Hospital of Dalian Medical University, Liaoning 116011, China.
Renwang PuDepartment of Radiology, First Affiliated Hospital of Dalian Medical University, Liaoning 116011, China.
Huizhi CaoDepartment of Radiology, First Affiliated Hospital of Dalian Medical University, Liaoning 116011, China.
Yijun LiuDepartment of Radiology, First Affiliated Hospital of Dalian Medical University, Liaoning 116011, China.
Dalian Medical University · CNFirst Affiliated Hospital of Dalian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To exploit material decomposition analysis in dual-energy spectral computed tomography (CT) to assess the blood supply status of the ground-glass opacity (GGO) in lungs. Materials and Methods: This retrospective study included 48 patients with lung adenocarcinoma, who underwent a contrast-enhanced dual-energy spectral CT scan before treatment (53 GGOs in total). The iodine concentration (IC) and water content (WC) of the GGO, the contralateral and ipsilateral normal lung tissues were measured in the arterial phase (AP) and their differences were analyzed. IC, normalized IC (NIC), and WC values were compared between the pure ground-glass opacity (pGGO) and the mixed ground-glass opacity (mGGO), and between the group of preinvasive lesions and the minimally invasive adenocarcinoma (MIA) and invasive adenocarcinoma (IA) groups. Results: The values of pGGO (IC = 20.9 ± 6.2 mg/mL and WC = 345.1 ± 87.1 mg/mL) and mGGO (IC = 23.8 ± 8.3 mg/mL and WC = 606.8 ± 124.5 mg/mL) in the AP were significantly higher than those of the contralateral normal lung tissues (IC = 15.0 ± 4.9 mg/mL and WC = 156.4 ± 36.8 mg/mL; IC = 16.2 ± 5.7 mg/mL and WC = 169.4 ± 41.0 mg/mL) and ipsilateral normal lung tissues (IC = 15.1 ± 6.2 mg/mL and WC = 156.3 ± 38.8 mg/mL; IC = 15.9 ± 6.0 mg/mL and WC = 174.7 ± 39.2 mg/mL; all Conclusion: Using dual-energy spectral CT and material decomposition analysis, the IC in GGO can be quantitatively measured which can be an indicator of the blood supply status in the GGO.

Indexed as

Multidetector Computed TomographyAdenocarcinomaAdenocarcinoma of LungArteriesFemaleHumansIodineLungLung NeoplasmsMaleMiddle AgedRetrospective StudiesWaterIodineWaterBlood supplyDual-energyGround-glass noduleLung adenocarcinomaMultidetector computed tomographySpectral CT

Identifiers

PMID29354009
PMCPMC5768493
OpenAlexW2783416732

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.