Evidence map›Paper›PMID 29353998›Full record

ArticleKorean journal of radiology

Diffusion-Weighted MRI for the Initial Viability Evaluation of Parasites in Hepatic Alveolar Echinococcosis: Comparison with Positron Emission Tomography.

Jianjun Zheng, Jing Wang, Jianqing Zhao, Xianyun Meng

Open access · hybridAbstract read
In one paragraph

Article in Korean journal of radiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Jianjun ZhengDepartment of Radiology, Ningbo N.2 Hospital, Ningbo, Zhejiang 315000, China.
Jing WangImaging Center, First Teaching Hospital, Xinjiang Medical University, Urumqi, Xinjiang 830054, China.
Jianqing ZhaoImaging Center, First Teaching Hospital, Xinjiang Medical University, Urumqi, Xinjiang 830054, China.
Xianyun MengDepartment of Radiology, Ningbo N.2 Hospital, Ningbo, Zhejiang 315000, China.
Xinjiang Medical University · CNNingbo No. 2 Hospital · CNNingbo No.6 Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: More than 70% of hepatic alveolar echinococcosis (HAE) are inoperable. Thus, long-term, or even life-long, pharmacological treatment with benzimidazoles is necessary. For effective treatment, it is of great importance to employ imaging techniques to detect and monitor the non-resectable parasitic viability. Therefore, this study aimed to evaluate diffusion-weighted imaging (DWI) in assessing the viability of HAE in comparison to 18-fluoro-deoxyglucose (18F-FDG) positron emission tomography, combined with computed tomography (PET/CT). Materials and Methods: Positron emission tomography, computed tomography and DWI (b-values: 0, 800 s/mm Results: A total of 14 HAE lesions were detected. Eight lesions (diameter 3-15 cm) showed perilesional hyper-signal intensity on DWI. This was visualised on PET/CT as increased FDG uptake. They mainly existed in the lesion's border with normal liver parenchyma. Five lesions (diameter < 2 cm) were detected as nodular hyperintensity on DWI and a 'hot spot' on PET/CT in the same distribution. One patient, who had received oral drug therapy for three years showed significantly decreased perilesional hyperintensity on the DWI and a hepatic defect without any FDG uptake on PET/CT. Pearson's correlation coefficient indicated a significant inverse correlation of the ADC and the SUV Conclusion: Diffusion-weighted imaging is capable of offering information on visually detecting the HAE lesions' viability and may be useful for routine application in the initial diagnosis of HAE.

Indexed as

Positron Emission Tomography Computed TomographyAdolescentAdultAnimalsDiffusion Magnetic Resonance ImagingEchinococcosis, HepaticFemaleFluorodeoxyglucose F18HumansMaleMiddle AgedRadiopharmaceuticalsRetrospective StudiesFluorodeoxyglucose F18RadiopharmaceuticalsDiffusion-weighted imagingEchinococcosisLiverMRIPET/CT

Identifiers

PMID29353998
PMCPMC5768505
OpenAlexW2783108468

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.