Evidence map›Paper›PMID 29353634›Full record

ArticleEuropean journal of oncology nursing : the official journal of European Oncology Nursing Society2018

Differences in symptom clusters before and twelve months after breast cancer surgery.

Melissa Mazor, Janine K Cataldo, Kathryn Lee, Anand Dhruva, Bruce Cooper, Steven M Paul, Kimberly Topp, Betty J Smoot, Laura B Dunn, Jon D Levine and 2 more

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of oncology nursing : the official journal of European Oncology Nursing Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. The prevalence and risk of symptom and function clusters in colorectal cancer survivors.Journal of cancer survivorship : research and practice · 2022
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Melissa MazorSchool of Nursing, University of California, San Francisco, CA, United States.
Janine K CataldoSchool of Nursing, University of California, San Francisco, CA, United States.
Kathryn LeeSchool of Nursing, University of California, San Francisco, CA, United States.
Anand DhruvaSchool of Medicine, United States.
Bruce CooperSchool of Nursing, University of California, San Francisco, CA, United States.
Steven M PaulSchool of Nursing, University of California, San Francisco, CA, United States.
Kimberly ToppSchool of Medicine, United States.
Betty J SmootSchool of Medicine, United States.
Laura B DunnSchool of Medicine, Stanford University, Stanford, CA, United States.
Jon D LevineSchool of Medicine, United States.
Yvette P ConleySchool of Nursing, University of Pittsburgh, Pittsburgh, PA, United States.
Christine MiaskowskiSchool of Nursing, University of California, San Francisco, CA, United States. Electronic address: chris.miaskowski@ucsf.edu.

Funding

UCSF CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTEUL1RR024131 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSTON, S. CLAIBORNE · 2006 to 2011
$111.2M
NURSING RESEARCH TRAINING IN SYMPTOM MANAGEMENTT32NR007088 · NINR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LEE, KATHRYN · 1996 to 2015
$7.5M
Symptom Management After Breast Cancer SurgeryR01CA107091 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MIASKOWSKI, CHRISTINE A. · 2003 to 2008
$4.5M
Long-term Arm Morbidity Following Breast Cancer TreatmentR01CA118658 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MIASKOWSKI, CHRISTINE A. · 2006 to 2010
$3.5M
Advancing the Science of Symptom Management in Oncology PatientsK05CA168960 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MIASKOWSKI, CHRISTINE A. · 2013 to 2017
$453k
NCI NIH HHS K05 CA168960NCI NIH HHS R01 CA107091NCI NIH HHS R01 CA118658NCRR NIH HHS UL1 RR024131NINR NIH HHS T32 NR007088
6 · The paper itself

Abstract

purposeGiven the inter-relatedness among symptoms, research efforts are focused on an evaluation of symptom clusters. The purposes of this study were to evaluate for differences in the number and types of menopausal-related symptom clusters assessed prior to and at 12-months after surgery using ratings of occurrence and severity and to evaluate for changes in these symptom clusters over time.

methodsPrior to and at 12 months after surgery, 392 women with breast cancer completed the Menopausal Symptoms Scale. Exploratory factor analyses were used to identify the symptom clusters.

resultsOf the 392 women evaluated, the mean number of symptoms (out of 46) was 13.2 (±8.5) at enrollment and 10.9 (±8.2) at 12 months after surgery. Using occurrence and severity, three symptom clusters were identified prior to surgery. Five symptom clusters were identified at 12 months following surgery. Two symptom clusters (i.e., pain/discomfort and hormonal) were relatively stable across both dimensions and time points. Two symptom clusters were relatively stable across both dimensions either prior to surgery (i.e., sleep/psychological/cognitive) or at 12 months after surgery (i.e., sleep). The other four clusters (i.e., irritability, psychological/cognitive, cognitive, psychological) were identified at one time point using a single dimension.

conclusionsWhile some menopausal-related symptom clusters were consistent across time and dimensions, the majority of symptoms clustered together differently depending on whether they were evaluated prior to or at 12 months after breast cancer surgery. An increased understanding of how symptom clusters change over time may assist clinicians to focus their symptom assessments and management strategies.

Indexed as

SyndromeAdultAgedBreast NeoplasmsCancer SurvivorsCluster AnalysisFactor Analysis, StatisticalFemaleFollow-Up StudiesHumansMenopauseMiddle AgedQuality of LifeSymptom AssessmentBreast cancerFactor analysisMenopauseSymptom clustersSymptoms

Identifiers

PMID29353634
PMCPMC5783198

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.