ArticleJournal of endocrinological investigation2018
Comparison of osteoporosis in US adults with type 1 and type 2 diabetes mellitus.
Article in Journal of endocrinological investigation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- Causal relationship between Type 1 diabetes and osteoporosis and fracture occurrence: a two-sample Mendelian randomization analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2023Pooled it
- Is diabetes mellitus a risk factor for low bone density: a systematic review and meta-analysis.BMC endocrine disorders · 2021Pooled it
- Is osteoporosis a risk factor for implant survival or failure?Evidence-based dentistry · 2018Pooled it
- Updated Advances on Drugs and Bone-Targeting Nanoparticles for Osteoporosis Therapy: Carrier Materials, Modification, Function Mechanism, and Applications-A Systematic Review.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Association between walking speed and multimorbidity patterns in community-dwelling older adults with diabetes and/or hypertension: a latent class analysis.Journal of diabetes and metabolic disorders · 2025Article
- Prevalence and risk factors for osteoporosis in type 1 diabetes-results from an observational study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025Observational
- Prevalence and Risk Factors of Osteoporosis: A Cross-Sectional Study in a Tertiary Center.Medicina (Kaunas, Lithuania) · 2024Article
- Urine-derived stem cell therapy for diabetes mellitus and its complications: progress and challenges.Endocrine · 2024Review
- Relationship between blood cadmium levels and bone mineral density in adults: a cross-sectional study.Frontiers in endocrinology · 2024Article
- Urine-derived stem cells-extracellular vesicles ameliorate diabetic osteoporosis through HDAC4/HIF-1α/VEGFA axis by delivering microRNA-26a-5p.Cell biology and toxicology · 2023Article
- Osteoporosis and sarcopenia are common and insufficiently diagnosed among chronic pancreatitis patients.BMC gastroenterology · 2023Article
- The association of opioid consumption and osteoporosis in old men: Bushehr Elderly Health (BEH) program.Archives of osteoporosis · 2022Article
- Factors associated with trabecular bone score in postmenopausal women with type 2 diabetes and normal bone mineral density.World journal of diabetes · 2022Article
- Evaluation of Bone Mineral Density, Serum Osteocalcin, and Osteopontin Levels in Postmenopausal Women with Type 2 Diabetes Mellitus, with/without Osteoporosis.Journal of osteoporosis · 2022Article
- Association of vitamin D receptor gene polymorphism with the occurrence of low bone density, osteopenia, and osteoporosis in patients with type 2 diabetes.Journal of diabetes and metabolic disorders · 2021Article
- Bone mineral density predictors in long-standing type 1 and type 2 diabetes mellitus.BMC endocrine disorders · 2021Article
- Gut Microbiota in Bone Health and Diabetes.Current osteoporosis reports · 2021Review
- Comparing the bone mineral density among male patients with latent autoimmune diabetes and classical type 1 and type 2 diabetes, and exploring risk factors for osteoporosis.Journal of endocrinological investigation · 2021Article
- The Correlation of Type 2 Diabetes Status with Bone Mineral Density in Middle-Aged Adults.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020Article
- Liraglutide increases bone formation and inhibits bone resorption in rats with glucocorticoid-induced osteoporosis.Journal of endocrinological investigation · 2019Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe examined bone mineral density (BMD) and osteoporosis prevalence in those with type 1 compared to type 2 diabetes derived from a nationally representative sample from the civilian community in the United States.
methodsData from the National Health and Nutrition Examination Survey (NHANES) for 2005-2006, 2007-2008, 2009-2010, and 2013-2014 were merged to obtain a large sample of diabetics at least 20 years of age with participation in the interview and medical examination. Osteoporosis status was defined by BMD at the total femur, femoral neck, or total lumbar spine. Self-reported diabetics that were prescribed insulin within the first year of diagnosis, are currently taking insulin, and reported no prescriptions for any diabetic pills were classified as type 1. Remaining self-reported diabetics were deemed as having type 2.
resultsA total of 2050 diabetics were included in which 87 (4%) were classified as type 1. Type 1 diabetics were found to have a significantly lower BMD at the total femur and femoral neck, but not at the lumbar spine in the adjusted models. Diabetics with type 1 were 4.7 times more likely to have osteoporosis than those with type 2. There was no significant relationship between diabetes type and BMD or osteoporosis prior to adjustment for confounders.
conclusionsAlthough our results show an increased likelihood of osteoporosis among those with type 1 diabetes, future studies including a larger sample from a community population are needed. It may benefit diabetics, especially those with type 1, to initiate osteoporosis screening methods including evaluation of fracture risk, bone quality, and BMD measurements at multiple sites earlier than recommended.
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