Evidence map›Paper›PMID 29352540›Full record

ArticleWorld psychiatry : official journal of the World Psychiatric Association (WPA)2018

Insight in schizophrenia spectrum disorders: relationship with behavior, mood and perceived quality of life, underlying causes and emerging treatments.

Paul H Lysaker, Michelle L Pattison, Bethany L Leonhardt, Scott Phelps, Jenifer L Vohs

Registry-linked trialOpen access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World psychiatry : official journal of the World Psychiatric Association (WPA), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04104347 (Does Metacognitive Training Improve Insight and Clinical Outcomes in Schizophrenia?), which is not on this map. Cited by 91 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed, 3 pooled it
17.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04104347 naunknown statusnot on this mapstarted 2019, after this paper: background citation

Does Metacognitive Training Improve Insight and Clinical Outcomes in Schizophrenia?

TypeinterventionalSponsorInstituto de Investigación Sanitaria de la Fundación Jiménez DíazRan2019 to 2021Enrolled252ConditionsSchizophrenia Spectrum and Other Psychotic DisordersArmsMetacognitive training (MCT), Support group
3 · Its place in the literature

Who cites it

91 citing papers in PubMed, 3 syntheses or guidelines pooled it, 228 citations in OpenAlex.

  1. Pooled it
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  8. Article
  9. Efficacy of metacognitive therapies in first-episode psychosis: a systematic review.Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater · 2026
    Article
  10. Article
  11. Review
  12. Observational
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  14. Poor insight and self-disorders in schizophrenia: an empirical study.European archives of psychiatry and clinical neuroscience · 2026
    Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Schizophrenia.Nature reviews. Disease primers · 2025
    Review
  20. Review

31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Paul H LysakerRoudebush VA Medical Center, Indiana University School of Medicine, Indianapolis, IN, USA.
Michelle L PattisonCollege of Applied Behavioral Sciences, University of Indianapolis, Indianapolis, IN, USA.
Bethany L LeonhardtIndiana University School of Medicine, Eskenazi Health-Midtown Community Mental Health, Indianapolis, IN, USA.
Scott PhelpsWesleyan University, Middletown, CT, USA.
Jenifer L VohsIndiana University School of Medicine, Indianapolis, IN, USA.
Indiana University – Purdue University Indianapolis · USIndiana University School of MedicineUniversity of Indianapolis · USWesleyan University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Poor insight in schizophrenia is prevalent across cultures and phases of illness. In this review, we examine the recent research on the relationship of insight with behavior, mood and perceived quality of life, on its complex roots, and on the effects of existing and emerging treatments. This research indicates that poor insight predicts poorer treatment adherence and therapeutic alliance, higher symptom severity and more impaired community function, while good insight predicts a higher frequency of depression and demoralization, especially when coupled with stigma and social disadvantage. This research also suggests that poor insight may arise in response to biological, experiential, neuropsychological, social-cognitive, metacognitive and socio-political factors. Studies of the effects of existing and developing treatments indicate that they may influence insight. In the context of earlier research and historical models, these findings support an integrative model of poor insight. This model suggests that insight requires the integration of information about changes in internal states, external circumstances, others' perspectives and life trajectory as well as the multifaceted consequences and causes of each of those changes. One implication is that treatments should, beyond providing education, seek to assist persons with schizophrenia to integrate the broad range of complex and potentially deeply painful experiences which are associated with mental illness into their own personally meaningful, coherent and adaptive picture.

Indexed as

antipsychotic medicationdepressionInsightmetacognitionneurocognitionpsychotherapyquality of liferecoveryschizophreniasocial cognitionstigmatherapeutic alliancetreatment adherence

Identifiers

PMID29352540
PMCPMC5775127
OpenAlexW2792686706

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.