Evidence map›Paper›PMID 29352424›Full record

ArticleNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics2018

Cannabinoid CB1 and CB2 Receptors, and Monoacylglycerol Lipase Gene Expression Alterations in the Basal Ganglia of Patients with Parkinson's Disease.

Francisco Navarrete, M Salud García-Gutiérrez, Auxiliadora Aracil-Fernández, José L Lanciego, Jorge Manzanares

Open access · bronzeAbstract read
In one paragraph

Article in Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it, 83 citations in OpenAlex.

  1. Pooled it
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  9. Mechanisms of Abnormal Lipid Metabolism in the Pathogenesis of Disease.International journal of molecular sciences · 2024
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  15. Characterization of the Antitumor Potential of Extracts ofInternational journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Francisco NavarreteInstituto de Neurociencias, Miguel Hernández University-CSIC, San Juan de Alicante, Alicante, Spain.
M Salud García-GutiérrezInstituto de Neurociencias, Miguel Hernández University-CSIC, San Juan de Alicante, Alicante, Spain.
Auxiliadora Aracil-FernándezInstituto de Neurociencias, Miguel Hernández University-CSIC, San Juan de Alicante, Alicante, Spain.
José L LanciegoCentro de Investigación Médica Aplicada, División de Neurociencias (CIMA-CIBERNED), Universidad de Navarra, Pamplona, Spain.
Jorge ManzanaresInstituto de Neurociencias, Miguel Hernández University-CSIC, San Juan de Alicante, Alicante, Spain. jmanzanares@goumh.umh.es.ORCID 0000-0002-4681-1533
Universitat de Miguel Hernández d'Elx · ESBiomedical Research Networking Center on Neurodegenerative Diseases · ESInstituto de Salud Carlos III · ES

Funding

Secretaría de Estado de Investigación, Desarrollo e Innovación BFU2012-37907
6 · The paper itself

Abstract

Previous studies suggest that the endocannabinoid system plays an important role in the neuropathological basis of Parkinson's disease (PD). This study was designed to detect potential alterations in the cannabinoid receptors CB1 (CB

Indexed as

Gene ExpressionAdultAgedAged, 80 and overAstrocytesBasal GangliaDopaminergic NeuronsFemaleHumansMaleMicrogliaMiddle AgedMonoacylglycerol LipasesParkinson DiseasePutamenReceptor, Cannabinoid, CB1Monoacylglycerol LipasesReceptor, Cannabinoid, CB1Receptor, Cannabinoid, CB2Basal gangliaCB1 and CB2 receptorGene expressionImmunohistochemistryMAGLParkinson’s disease

Identifiers

PMID29352424
PMCPMC5935636
OpenAlexW2785736130

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.