Evidence map›Paper›PMID 29352381›Full record

ArticleEuropean radiology2018

Myocardial perfusion in patients with suspected coronary artery disease: comparison between 320-MDCT and rubidium-82 PET.

Roberto Nery Dantas, Antonildes Nascimento Assuncao, Ismar Aguiar Marques, Mateus Guimaraes Fahel, Cesar Higa Nomura, Luiz Francisco Rodrigues Avila, Maria Clementina Pinto Giorgi, Jose Soares, Jose Claudio Meneghetti, Jose Rodrigues Parga

Abstract readEvaluation Study
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In one paragraph

Article in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  4. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Roberto Nery DantasComputed Tomography Department, Heart Institute, InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil. nerydjr@hotmail.com.
Antonildes Nascimento AssuncaoComputed Tomography Department, Heart Institute, InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil.
Ismar Aguiar MarquesComputed Tomography Department, Heart Institute, InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil.
Mateus Guimaraes FahelComputed Tomography Department, Heart Institute, InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil.
Cesar Higa NomuraComputed Tomography Department, Heart Institute, InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil.
Luiz Francisco Rodrigues AvilaComputed Tomography Department, Heart Institute, InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil.
Maria Clementina Pinto GiorgiDepartment of Nuclear Medicine and Molecular Imaging, Heart Institute, InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil.
Jose SoaresDepartment of Nuclear Medicine and Molecular Imaging, Heart Institute, InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil.
Jose Claudio MeneghettiDepartment of Nuclear Medicine and Molecular Imaging, Heart Institute, InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil.
Jose Rodrigues PargaComputed Tomography Department, Heart Institute, InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesDespite advances in non-invasive myocardial perfusion imaging (MPI) evaluation, computed tomography (CT) multiphase MPI protocols have not yet been compared with the highly accurate rubidium-82 positron emission tomography (

methodsForty-four patients referred for MPI evaluation were prospectively enrolled and underwent dipyridamole stress

resultsThere was high agreement for recognizing summed stress scores ≥ 4 (kappa 0.77, 95% CI 0.55-0.98, p < 0.001) and moderate for detecting SDS ≥ 2 (kappa 0.51, 95% CI 0.23-0.80, p < 0.001). In a per segment analysis, agreement was high for the presence of perfusion defects during stress and rest (kappa 0.75 and 0.82, respectively) and was moderate for impairment severity (kappa 0.58 and 0.65, respectively). The 320-CT protocol was safe, with low radiation burden (9.3 ± 2.4 mSv).

conclusionsThere was a significant agreement between dipyridamole stress 320-CT MPI and KEY POINTS: • Rubidium-82 PET and 320-MDCT can perform MPI studies for CAD investigation. • There is high agreement between rubidium-82 PET and 320-MDCT for MPI assessment. • Multiphase CT perfusion protocols are feasible and with low radiation. • Multiphase CT perfusion protocols can identify image artefacts.

Indexed as

RadiopharmaceuticalsRubidium RadioisotopesComputed Tomography AngiographyCoronary Artery DiseaseCoronary VesselsDipyridamoleFemaleHumansMaleMiddle AgedMultidetector Computed TomographyMyocardial Perfusion ImagingPositron-Emission TomographyProspective StudiesSoftwareTomography, Emission-Computed, Single-PhotonDipyridamoleRadiopharmaceuticalsRubidium-82Rubidium RadioisotopesVasodilator AgentsCoronary artery diseaseMyocardial perfusion imagingPositron emission tomographyRubidium radioisotopesTomography

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.