Evidence map›Paper›PMID 29352372›Full record

ArticleMolecular imaging and biology2018

Improving PET Quantification of Small Animal [

Jacobo Cal-Gonzalez, Juan José Vaquero, Joaquín L Herraiz, Mailyn Pérez-Liva, María Luisa Soto-Montenegro, Santiago Peña-Zalbidea, Manuel Desco, José Manuel Udías

Open access · hybridAbstract read
PubMed Publisher
In one paragraph

Article in Molecular imaging and biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Impact of tissue-independent positron range correction on [European journal of nuclear medicine and molecular imaging · 2025
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  15. Evaluation of aMolecules (Basel, Switzerland) · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Jacobo Cal-GonzalezQIMP group, Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria. jacobo.calgonzalez@meduniwien.ac.at.ORCID 0000-0001-6286-0768
Juan José VaqueroDepartamento de Bioingeniería e Ingeniería Aeroespacial, Universidad Carlos III de Madrid, Madrid, Spain.
Joaquín L HerraizGrupo de Física Nuclear, Dpto. Física Atómica, Molecular y Nuclear, Universidad Complutense de Madrid, CEI Moncloa, Madrid, Spain.
Mailyn Pérez-LivaGrupo de Física Nuclear, Dpto. Física Atómica, Molecular y Nuclear, Universidad Complutense de Madrid, CEI Moncloa, Madrid, Spain.
María Luisa Soto-MontenegroInstituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.
Santiago Peña-ZalbideaDepartamento de Bioingeniería e Ingeniería Aeroespacial, Universidad Carlos III de Madrid, Madrid, Spain.
Manuel DescoDepartamento de Bioingeniería e Ingeniería Aeroespacial, Universidad Carlos III de Madrid, Madrid, Spain.
José Manuel UdíasGrupo de Física Nuclear, Dpto. Física Atómica, Molecular y Nuclear, Universidad Complutense de Madrid, CEI Moncloa, Madrid, Spain.
Universidad Complutense de Madrid · ESHospital General Universitario Gregorio Marañón · ESSpanish National Centre for Cardiovascular Research · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeImage quality of positron emission tomography (PET) tracers that emits high-energy positrons, such as Ga-68, Rb-82, or I-124, is significantly affected by positron range (PR) effects. PR effects are especially important in small animal PET studies, since they can limit spatial resolution and quantitative accuracy of the images. Since generators accessibility has made Ga-68 tracers wide available, the aim of this study is to show how the quantitative results of [ PROCEDURES: Eighteen scans in 12 mice were evaluated, with three different models of tumors: PC12, AR42J, and meningiomas. In addition, three different [

resultsAll TLR values in the PRC images were significantly different (p < 0.05) than the ones from non-PRC images. The relative differences of the tumor TLR values, respect to the case with no PRC, were ΔTLR

conclusionThe PRC methods proposed provide a significant quantitative improvement in [

Indexed as

ElectronsPositron Emission Tomography Computed TomographyAnimalsGallium RadioisotopesMaleMice, NudePhantoms, ImagingTumor BurdenGallium-68Gallium Radioisotopes[68Ga]DOTA-labeled radiotracersPET image reconstructionPositron range correctionSmall animal PET/CT

Identifiers

PMID29352372
OpenAlexW2789008552

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.