Evidence map›Paper›PMID 29352332›Full record

ArticleInternational orthopaedics2018

Effects of continuous or intermittent low-magnitude high-frequency vibration on fracture healing in sheep.

Yanhui Li, Guozhao Liu, Jing Yu, Chen Li, Lei Tan, Baohui Hao, Chao Liu, Junhao Lin, Dong Zhu, Xizheng Zhang

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Article in International orthopaedics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Yanhui LiDepartment of Cardiology and Echocardiography, First Hospital of Jilin University, Changchun, China.
Guozhao LiuCollege of Mechanical Science and Engineering, Jilin University, Changchun, China.
Jing YuOperating Theatre 1, The First Hospital of Jilin University, Changchun, China.
Chen LiDepartment of Orthopedic Traumatology, First Hospital of Jilin University, Changchun, 130021, China.
Lei TanDepartment of Orthopedic Traumatology, First Hospital of Jilin University, Changchun, 130021, China.
Baohui HaoDepartment of Orthopedic Traumatology, First Hospital of Jilin University, Changchun, 130021, China.
Chao LiuDepartment of Orthopedic Traumatology, First Hospital of Jilin University, Changchun, 130021, China.
Junhao LinCollege of Mechanical Science and Engineering, Jilin University, Changchun, China.
Dong ZhuDepartment of Orthopedic Traumatology, First Hospital of Jilin University, Changchun, 130021, China. swyxgc@126.com.
Xizheng ZhangInstitute of Medical Equipment, Academy of Military Medical Sciences, Tianjin, China.
Jilin University · CNFirst Hospital of Jilin University · CNAcademy of Military Medical Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeVibration therapy has been shown to improve fracture healing. In this study, we investigated the effects of continuous or different intermittent vibration regimens on fracture healing in sheep models on the basis of radiographs, mechanical, and biochemical testing.

methodsThe 63 right-hind metatarsals from 63 sheep (12-month-old) were osteotomized; followed by surgical fixation with a steel plate. Two weeks after the surgery, the sheep with right-hind metatarsal fractures were randomly divided into seven groups (n=9/group): control (no vibration treated), continuous vibration (CV), one, three, five, seven and 14-day intermittent vibration (named IV-1, -3, -5, -7, and -14, respectively) groups, which represented a cycle of the successive n-day vibration and successive n-day break. Vibration stimulation (F=35 Hz, a=0.25 g) lasted 15 minutes each treatment. After eight weeks with/without vibration treatment, the sheep were euthanized with intravenous anesthetic. The callus formation, mechanical properties, and biochemical compositions of fracture metatarsals were analyzed.

resultsIn CV and IV-7 groups, X-ray images showed an increased callus volume around the fracture area. The bone elastic modulus and the concentrations of Ca, P, and Ca/P ratio of the area at 15 and 25 mm away from the fracture centerline were higher in CV and IV-7 groups compared with the other groups.

conclusionsOur results demonstrate that both CV and IV-7 vibration patterns showed better improvement of fracture healing.

Indexed as

AnimalsBony CallusDisease Models, AnimalFemaleFracture HealingFractures, BoneMetatarsal BonesSheepVibrationContinuous or intermittent vibrationFracture healingMechanical and biochemical propertiesX-ray imaging

Identifiers

PMID29352332
OpenAlexW2792454673

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.