Evidence map›Paper›PMID 29352234›Full record

ArticleScientific reports2018

Bi-exponential 3D-T1ρ mapping of whole brain at 3 T.

Rajiv G Menon, Azadeh Sharafi, Johannes Windschuh, Ravinder R Regatte

Abstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Optimization of spin-lock times for TScientific reports · 2022
    Article
  10. Article
  11. Performance Comparison of Compressed Sensing Algorithms for Accelerating TJournal of magnetic resonance imaging : JMRI · 2021
    Article
  12. Article
  13. Three-Dimensional GRE TMagnetic resonance in medicine · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rajiv G MenonBernard and Irene Schwartz Center for Biomedical Imaging, New York University School of Medicine, New York, NY, USA. rajiv.menon@nyumc.org.ORCID http://orcid.org/0000-0001-6160-886X
Azadeh SharafiBernard and Irene Schwartz Center for Biomedical Imaging, New York University School of Medicine, New York, NY, USA.ORCID http://orcid.org/0000-0001-9572-4922
Johannes WindschuhBernard and Irene Schwartz Center for Biomedical Imaging, New York University School of Medicine, New York, NY, USA.
Ravinder R RegatteBernard and Irene Schwartz Center for Biomedical Imaging, New York University School of Medicine, New York, NY, USA.

Funding

TR&D 4: Revealing Microstructure: Biophysical modeling and validation for discovery and clinical careP41EB017183 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Hersh Chandarana · 2014 to 2026
$19.3M
Imaging Biomarkers of Knee OsteoarthritisR01AR068966 · NIAMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI REGATTE, RAVINDER · 2016 to 2021
$3.1M
Sodium MRI for Assessment of Early OA.R01AR060238 · NIAMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI REGATTE, RAVINDER · 2011 to 2015
$2.9M
Assessment of Cartilage Repair with Sodium MRI at 3TR01AR067156 · NIAMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI REGATTE, RAVINDER · 2015 to 2019
$2.3M
NIAMS NIH HHS R01 AR060238NIAMS NIH HHS R01 AR067156NIAMS NIH HHS R01 AR068966NIBIB NIH HHS P41 EB017183
6 · The paper itself

Abstract

Detection of multiple relaxation pools using MRI is useful in a number of neuro-pathologies including multiple sclerosis (MS), Alzheimer's, and stroke. In this study we evaluate the feasibility of using T1ρ imaging for the detection of bi-exponential decays in the human brain. A prospective T1ρ imaging study was performed on model relaxation phantoms (eggs) and 7 healthy volunteers. The data was fitted using a single pool and a 2-pool model to estimate mono- and bi-exponential T1ρ maps, respectively. Bi-exponential decays were identified in the gray matter (GM) and white matter (WM) of the brain with 40.5% of GM, and 65.1% of WM pixels showing two T1ρ relaxation pools (significance level P < 0.05). Detection of T1ρ based bi-exponential decays in the brain provides complimentary information to T

Indexed as

Brain MappingMagnetic Resonance ImagingAdultBrainFemaleHumansImage Processing, Computer-AssistedMaleMultiple SclerosisPhantoms, ImagingYoung Adult

Identifiers

PMID29352234
PMCPMC5775253

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.