Evidence map›Paper›PMID 29352212›Full record

ArticleCell death & disease2018

Rare mutations in apoptosis related genes APAF1, CASP9, and CASP3 contribute to human neural tube defects.

Xiangyu Zhou, Weijia Zeng, Huili Li, Haitao Chen, Gang Wei, Xueyan Yang, Ting Zhang, Hongyan Wang

Open access · goldAbstract readLetter
In one paragraph

Article in Cell death & disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Bhlhe40/Sirt1 Axis-Regulated Mitophagy Is Implicated in All-Frontiers in cell and developmental biology · 2021
    Article
  10. Caspases in the Developing Central Nervous System: Apoptosis and Beyond.Frontiers in cell and developmental biology · 2021
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Xiangyu ZhouObstetrics & Gynecology Hospital, Institute of Reproduction and Development, State Key Laboratory of Genetic Engineering at School of Life Sciences, Fudan University, 200011, Shanghai, China. husq04@163.com.
Weijia ZengObstetrics & Gynecology Hospital, Institute of Reproduction and Development, State Key Laboratory of Genetic Engineering at School of Life Sciences, Fudan University, 200011, Shanghai, China.
Huili LiCapital Institute of Pediatrics, 100020, Beijing, China.
Haitao ChenObstetrics & Gynecology Hospital, Institute of Reproduction and Development, State Key Laboratory of Genetic Engineering at School of Life Sciences, Fudan University, 200011, Shanghai, China.
Gang WeiObstetrics & Gynecology Hospital, Institute of Reproduction and Development, State Key Laboratory of Genetic Engineering at School of Life Sciences, Fudan University, 200011, Shanghai, China.
Xueyan YangObstetrics & Gynecology Hospital, Institute of Reproduction and Development, State Key Laboratory of Genetic Engineering at School of Life Sciences, Fudan University, 200011, Shanghai, China.
Ting ZhangCapital Institute of Pediatrics, 100020, Beijing, China.
Hongyan WangObstetrics & Gynecology Hospital, Institute of Reproduction and Development, State Key Laboratory of Genetic Engineering at School of Life Sciences, Fudan University, 200011, Shanghai, China. wanghylab@fudan.edu.cn.
Fudan University · CNCapital Institute of Pediatrics · CNState Key Laboratory of Genetic Engineering

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

MutationAmino Acid SequenceApoptosisApoptotic Protease-Activating Factor 1Asian PeopleCaspase 3Caspase 9HEK293 CellsHumansNeural Tube DefectsAPAF1 protein, humanApoptotic Protease-Activating Factor 1CASP3 protein, humanCASP9 protein, humanCaspase 3Caspase 9

Identifiers

PMID29352212
PMCPMC5833651
OpenAlexW2793547516

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.