Evidence map›Paper›PMID 29352184›Full record

ArticleScientific reports2018

Expression and relevance of the G protein-gated K

Allison Anderson, Kanchan Kulkarni, Ezequiel Marron Fernandez de Velasco, Nicholas Carlblom, Zhilian Xia, Atsushi Nakano, Kirill A Martemyanov, Elena G Tolkacheva, Kevin Wickman

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 29 citations in OpenAlex.

  1. G protein-gated inwardly rectifying KHistology and histopathology · 2025
    Review
  2. Review
  3. Review
  4. Article
  5. JBMR plus · 2024
    Article
  6. Article
  7. Article
  8. Relevance ofInternational journal of molecular sciences · 2023
    Review
  9. Muscarinic acetylcholine receptors MFrontiers in cardiovascular medicine · 2023
    Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. GPCR-dependent biasing of GIRK channel signaling dynamics by RGS6 in mouse sinoatrial nodal cells.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  17. Inhibition of G protein-gated KScientific reports · 2020
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Allison AndersonDepartment of Pharmacology, University of Minnesota, Minneapolis, MN, 55455, USA.
Kanchan KulkarniDepartment of Biomedical Engineering, University of Minnesota, Minneapolis, MN, 55455, USA.
Ezequiel Marron Fernandez de VelascoDepartment of Pharmacology, University of Minnesota, Minneapolis, MN, 55455, USA.
Nicholas CarlblomDepartment of Pharmacology, University of Minnesota, Minneapolis, MN, 55455, USA.
Zhilian XiaDepartment of Pharmacology, University of Minnesota, Minneapolis, MN, 55455, USA.
Atsushi NakanoDepartment of Molecular, Cell & Developmental Biology, University of California, Los Angeles, CA, 90095, USA.
Kirill A MartemyanovDepartment of Neuroscience, The Scripps Research Institute, Jupiter, FL, 33458, USA.
Elena G TolkachevaDepartment of Biomedical Engineering, University of Minnesota, Minneapolis, MN, 55455, USA.
Kevin WickmanDepartment of Pharmacology, University of Minnesota, Minneapolis, MN, 55455, USA. wickm002@umn.edu.
University of Minnesota · USScripps Research Institute · USUniversity of California, Los Angeles · US

Funding

The role of RGS proteins in the parasympathetic control of heart rateR01HL105550 · NHLBI · UNIVERSITY OF MINNESOTA · PI MARTEMYANOV, KIRILL A., WICKMAN, KEVIN D · 2011 to 2018
$3.2M
Hemogenic endocardium: contribution to the valvular tissue macrophagesR01HL127427 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI NAKANO, ATSUSHI · 2016 to 2019
$1.5M
Molecular Basis of RGS Protein Function in the StriatumK02DA026405 · NIDA · UNIVERSITY OF MINNESOTA · PI MARTEMYANOV, KIRILL A. · 2009 to 2019
$1.2M
The role of electromechanical cue on cardiomyocyte maturationR21HL124503 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GIMZEWSKI, JAMES K, NAKANO, ATSUSHI · 2015 to 2016
$407k
Novel entropy based identification of rotors in human atrial fibrillationR21HL128790 · NHLBI · UNIVERSITY OF MINNESOTA · PI MULPURU, SIVA K, TALKACHOVA, ALENA · 2016 to 2017
$232k
Targeting the parasympathetic regulation of the heart to treat arrhythmiasF31HL139090 · NHLBI · UNIVERSITY OF MINNESOTA · PI ANDERSON, ALLISON DIANE · 2017 to 2019
$120k
NHLBI NIH HHS F31 HL139090NHLBI NIH HHS R01 HL105550NHLBI NIH HHS R01 HL127427NHLBI NIH HHS R21 HL124503NHLBI NIH HHS R21 HL128790NIDA NIH HHS K02 DA026405
6 · The paper itself

Abstract

The atrial G protein-gated inwardly rectifying K

Indexed as

Gene ExpressionIon Channel GatingAction PotentialsAnimalsArrhythmias, CardiacElectrocardiographyGenotypeG Protein-Coupled Inwardly-Rectifying Potassium ChannelsHeart AtriaHeart VentriclesMiceMice, KnockoutMuscle CellsProtein MultimerizationSignal TransductionVentricular FunctionG Protein-Coupled Inwardly-Rectifying Potassium Channels

Identifiers

PMID29352184
PMCPMC5775354
OpenAlexW2782877976

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.