Evidence map›Paper›PMID 29352093›Full record

ArticleJournal of the American Heart Association2018

Excessive Daytime Sleepiness Independently Predicts Increased Cardiovascular Risk After Myocardial Infarction.

Jiang Xie, Fatima H Sert Kuniyoshi, Naima Covassin, Prachi Singh, Apoor S Gami, C Anwar A Chahal, Virend K Somers

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 1 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 1 synthesis or guideline pooled it, 100 citations in OpenAlex.

  1. Efficacy of advancement treatments of the stomatognathic system on objective sleepiness in OSA: a systematic review.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Pooled it
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  3. Observational
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  9. Novel assessment of CPAP adherence data reveals distinct diurnal patterns.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
  10. Review
  11. Long-term health outcomes for patients with obstructive sleep apnea: placing the Agency for Healthcare Research and Quality report in context-a multisociety commentary.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024
    Article
  12. Article
  13. Article
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  15. Cardiovascular capacity in adults with obstructive sleep apnoea.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2023
    Article
  16. International Consensus Statement on Obstructive Sleep Apnea.International forum of allergy & rhinology · 2023
    Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Jiang XieDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN.
Fatima H Sert KuniyoshiDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN.
Naima CovassinDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN.
Prachi SinghDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN.
Apoor S GamiDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN.
C Anwar A ChahalDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN.
Virend K SomersDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN somers.virend@mayo.edu.
WinnMed · USMayo Clinic · US

Funding

Mayo Clinic Center for Clinical and Translational Science (CCaTS UL1 Supplement - Dr. Timothy Curry)UL1TR002377 · NCATS · MAYO CLINIC ROCHESTER · PI VESNA D GAROVIC · 2017 to 2026
$78.4M
Disease Mechanisms in Sleep ApneaR01HL065176 · NHLBI · MAYO CLINIC ROCHESTER · PI SOMERS, VIREND K · 1999 to 2021
$5.8M
Interactions Between Obesity Risk and Insufficient SleepR01HL114024 · NHLBI · MAYO CLINIC ROCHESTER · PI SOMERS, VIREND K · 2012 to 2015
$2.7M
Sleep Restriction and Augmented Vascular Risk in PrehypertensionR01HL114676 · NHLBI · MAYO CLINIC ROCHESTER · PI SOMERS, VIREND K · 2012 to 2016
$2.4M
NCATS NIH HHS UL1 TR002377NHLBI NIH HHS R01 HL065176NHLBI NIH HHS R01 HL114024NHLBI NIH HHS R01 HL114676
6 · The paper itself

Abstract

backgroundExcessive daytime sleepiness (EDS), a common symptom among patients with sleep-disordered breathing, is closely associated with the development of cardiovascular diseases, but its long-term prognostic value is not completely understood. The aim of this study was to investigate whether EDS would be an independent prognostic factor after myocardial infarction. METHODS AND

resultsWe prospectively recruited 112 post-myocardial infarction patients. The Epworth Sleepiness Scale was completed before polysomnography, and EDS was defined as a score ≥11. After exclusion of 8 patients who accepted treatment with continuous positive airway pressure, 104 patients were followed up for 48 months. The primary composite end point was major adverse cardiac events. Patients with EDS had higher rates of major adverse cardiac events (48.4% versus 27.4%, χ

conclusionsEDS may be an independent prognostic factor of adverse outcome in post-myocardial infarction patients with moderate to severe sleep-disordered breathing. Evaluation of EDS may shed new light on risk stratification and identify treatment responders for this patient population.

Indexed as

Circadian RhythmSleepAgedContinuous Positive Airway PressureDisorders of Excessive SomnolenceFemaleHumansMaleMiddle AgedMyocardial InfarctionPrognosisProspective StudiesRecurrenceRisk AssessmentRisk FactorsSeverity of Illness Indexexcessive daytime sleepinessmajor adverse cardiac eventmyocardial infarctionsleep disordered breathing

Identifiers

PMID29352093
PMCPMC5850153
OpenAlexW2793728633

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.