Evidence map›Paper›PMID 29352035›Full record

ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2018

Using mouse transgenic and human stem cell technologies to model genetic mutations associated with schizophrenia and autism.

David St Clair, Mandy Johnstone

Open access · hybridAbstract readReview
In one paragraph

Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Frontiers in cellular neuroscience · 2020
    Article
  8. Review
  9. Of mice and mental health: facilitating dialogue and seeing further.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2018
    Article
  10. ADNP Regulates Cognition: A Multitasking Protein.Frontiers in neuroscience · 2018
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

David St ClairInstitute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, UK d.stclair@abdn.ac.uk.ORCID 0000-0002-5890-7292
Mandy JohnstoneDivision of Psychiatry, University of Edinburgh, Royal Edinburgh Hospital, Edinburgh, UK.ORCID 0000-0002-8398-0862
Royal Edinburgh Hospital · GBUniversity of Aberdeen · GB

Funding

Fear memory attenuation: testing reconsolidation-extinction boundariesR01MH091147 · NIMH · UNIVERSITY OF TEXAS AT AUSTIN · PI MONFILS, MARIE H. · 2011 to 2015
$1.9M
Novel paradigm attenuates traumatic memories and prevents return of fearR21MH086805 · NIMH · UNIVERSITY OF TEXAS AT AUSTIN · PI MONFILS, MARIE H. · 2010 to 2011
$398k
NIMH NIH HHS R01 MH091147NIMH NIH HHS R21 MH086805Wellcome Trust 100135
6 · The paper itself

Abstract

Solid progress has occurred over the last decade in our understanding of the molecular genetic basis of neurodevelopmental disorders, and of schizophrenia and autism in particular. Although the genetic architecture of both disorders is far more complex than previously imagined, many key loci have at last been identified. This has allowed

Indexed as

Disease Models, AnimalMutationAnimalsAnimals, Genetically ModifiedAutistic DisorderHumansInduced Pluripotent Stem CellsMiceSchizophreniaautismmouse and iPSC modelsSchizophrenia

Identifiers

PMID29352035
PMCPMC5790834
OpenAlexW2783317872

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.