ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2018
Neuropharmacology of compulsive eating.
Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Exploring the utility of N-acetylcysteine for loss of control eating: protocol of an open-label single-arm pilot study.Pilot and feasibility studies · 2025Article
- A Pilot Study on the Effect of Added Sugar on Response Inhibition: Event-Related Potentials in a Go/NoGo Task.Medicina (Kaunas, Lithuania) · 2025Article
- Psilocybin-assisted psychotherapy as a potential treatment for eating disorders: a narrative review of preliminary evidence.Trends in psychiatry and psychotherapy · 2024Review
- Review
- Pharmacological strategies for appetite modulation in eating disorders: a narrative review.Consortium psychiatricum · 2023Review
- Assessment of Binge-Like Eating of Unsweetened vs. Sweetened Chow Pellets in BALB/c Substrains.Frontiers in behavioral neuroscience · 2022Article
- Obese Animals as Models for Numerous Diseases: Advantages and Applications.Medicina (Kaunas, Lithuania) · 2021Article
- Article
- Reward sensitivity deficits in a rat model of compulsive eating behavior.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2020Article
- Chronic stress increases susceptibility to food addiction by increasing the levels of DR2 and MOR in the nucleus accumbens.Neuropsychiatric disease and treatment · 2019Article
- Impulsive choice does not predict binge-like eating in rats.Behavioural pharmacology · 2018Article
- Defining Dysbiosis in Disorders of Movement and Motivation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Review
- Of mice and mental health: facilitating dialogue and seeing further.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2018Article
- Trace Amine Associated Receptor 1 (TAAR1) Modulation of Food Reward.Frontiers in pharmacology · 2018Review
- A behavioral and pharmacological characterization of palatable diet alternation in mice.Pharmacology, biochemistry, and behavior · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Compulsive eating behaviour is a transdiagnostic construct observed in certain forms of obesity and eating disorders, as well as in the proposed construct of 'food addiction'. Compulsive eating can be conceptualized as comprising three elements: (i) habitual overeating, (ii) overeating to relieve a negative emotional state, and (iii) overeating despite adverse consequences. Neurobiological processes that include maladaptive habit formation, the emergence of a negative affect, and dysfunctions in inhibitory control are thought to drive the development and persistence of compulsive eating behaviour. These complex psychobehavioural processes are under the control of various neuropharmacological systems. Here, we describe the current evidence implicating these systems in compulsive eating behaviour, and contextualize them within the three elements. A better understanding of the neuropharmacological substrates of compulsive eating behaviour has the potential to significantly advance the pharmacotherapy for feeding-related pathologies.This article is part of a discussion meeting issue 'Of mice and mental health: facilitating dialogue between basic and clinical neuroscientists'.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.