Evidence map›Paper›PMID 29351965›Full record

Trial reportPediatrics2018

Cost-effectiveness of Cognitive Behavioral Therapy for Depressed Youth Declining Antidepressants.

John F Dickerson, Frances L Lynch, Michael C Leo, Lynn L DeBar, John Pearson, Gregory N Clarke

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Article
  8. Economics and mental health: the current scenario.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2020
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

John F DickersonKaiser Permanente Center for Health Research, Portland, Oregon; and john.f.dickerson@kpchr.org.
Frances L LynchKaiser Permanente Center for Health Research, Portland, Oregon; and.
Michael C LeoKaiser Permanente Center for Health Research, Portland, Oregon; and.
Lynn L DeBarKaiser Permanente Washington Health Research Institute, Seattle, Washington.
John PearsonKaiser Permanente Center for Health Research, Portland, Oregon; and.
Gregory N ClarkeKaiser Permanente Center for Health Research, Portland, Oregon; and.
Kaiser Permanente Center for Health Research · USKaiser Permanente Washington Health Research Institute · US

Funding

Brief, Primary Care CBT for Unmedicated Depressed YouthR01MH073918 · NIMH · KAISER FOUNDATION RESEARCH INSTITUTE · PI CLARKE, GREGORY N · 2006 to 2010
$3.1M
NIMH NIH HHS R01 MH073918
6 · The paper itself

Abstract

BACKGROUND AND

objectivesAdolescents with depression identified in primary care settings often have limited treatment options beyond antidepressant (AD) therapy. We assessed the cost-effectiveness of a brief cognitive behavioral therapy (CBT) program among depressed adolescents who declined or quickly stopped using ADs.

methodsA total of 212 youth with depression were randomly assigned to treatment as usual (TAU) or TAU plus brief individual CBT. Clinical outcomes included depression-free days (DFDs) and estimated quality-adjusted life-years (QALYs). Costs were adjusted to 2008 US dollars. Incremental cost-effectiveness ratios (ICERs) comparing CBT to TAU were calculated over 12- and 24-month follow-up periods.

resultsYouth randomly assigned to CBT had 26.8 more DFDs (

conclusionsBrief primary care CBT among youth declining AD therapy is cost-effective by widely accepted standards in depression treatment. CBT becomes dominant over TAU over time, as revealed by a statistically significant cost offset at the end of the 2-year follow-up.

Indexed as

Cost-Benefit AnalysisAdolescentAntidepressive AgentsChildCognitive Behavioral TherapyDepressive DisorderFemaleFollow-Up StudiesHumansIntention to Treat AnalysisMaleQuality-Adjusted Life YearsAntidepressive Agents

Identifiers

PMID29351965
PMCPMC5810604
OpenAlexW2784570699

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.