Evidence map›Paper›PMID 29351884›Full record

ArticleRedox biology2018

Crucial role of chelatable iron in silver nanoparticles induced DNA damage and cytotoxicity.

Agnieszka Grzelak, Maria Wojewódzka, Sylwia Meczynska-Wielgosz, Mariusz Zuberek, Dominika Wojciechowska, Marcin Kruszewski

Open access · goldAbstract read
In one paragraph

Article in Redox biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 54 citations in OpenAlex.

  1. Review
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  4. HJournal of nanobiotechnology · 2024
    Article
  5. Ferroptosis: underlying mechanisms and involvement in neurodegenerative diseases.Apoptosis : an international journal on programmed cell death · 2024
    Review
  6. The Use of Metallic Nanoparticles in Wound Healing: New Perspectives.International journal of molecular sciences · 2022
    Article
  7. Review
  8. Review
  9. Review
  10. Potentially Bioactive Fungus Mediated Silver Nanoparticles.Nanomaterials (Basel, Switzerland) · 2021
    Article
  11. Incorporation of Silver Nanoparticles in Hydrogel Matrices for Controlling Wound Infection.Journal of burn care & research : official publication of the American Burn Association · 2021
    Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Bactericidal and Cytotoxic Properties of Silver Nanoparticles.International journal of molecular sciences · 2019
    Review
  19. Review
  20. CuO and CeOFrontiers in pharmacology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Agnieszka GrzelakDepartment of Molecular Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, Banacha 12/16, 90‑237 Lodz, Poland.
Maria WojewódzkaCentre for Radiobiology and Biological Dosimetry, Institute of Nuclear Chemistry and Technology, Dorodna 16, 03‑195 Warsaw, Poland.
Sylwia Meczynska-WielgoszCentre for Radiobiology and Biological Dosimetry, Institute of Nuclear Chemistry and Technology, Dorodna 16, 03‑195 Warsaw, Poland.
Mariusz ZuberekDepartment of Molecular Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, Banacha 12/16, 90‑237 Lodz, Poland.
Dominika WojciechowskaDepartment of Molecular Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, Banacha 12/16, 90‑237 Lodz, Poland.
Marcin KruszewskiCentre for Radiobiology and Biological Dosimetry, Institute of Nuclear Chemistry and Technology, Dorodna 16, 03‑195 Warsaw, Poland; Department of Molecular Biology and Translational Research, Institute of Rural Health, Jaczewskiego 2, 20‑090 Lublin, Poland; Faculty of Medicine, University of Information Technology and Management, ul. Sucharskiego 2, Rzeszów 35-225, Poland. Electronic address: m.kruszewski@ichtj.waw.pl.
University of Łódź · PLInstytut Chemii i Techniki Jądrowej · PLInstytut Medycyny Wsi im. Witolda Chodźki · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Damage to mitochondria and subsequent ROS leakage is a commonly accepted mechanism of nanoparticle toxicity. However, malfunction of mitochondria results in generation of superoxide anion radical (O

Indexed as

Cell ProliferationDNA DamageHep G2 CellsHumansHydrogen PeroxideIron Chelating AgentsMetal NanoparticlesMitochondriaReactive Oxygen SpeciesSilverSuperoxidesHydrogen PeroxideIron Chelating AgentsReactive Oxygen SpeciesSilverSuperoxidesFenton reactionIronMitochondriaNanoparticle toxicityROS generation

Identifiers

PMID29351884
PMCPMC5975067
OpenAlexW2783906684

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.