ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2018
Travelers' Diarrhea in Thailand: A Quantitative Analysis Using TaqMan® Array Card.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 43 citations in OpenAlex.
- Use of a TaqMan Array Card for identification of enterotoxins and colonization factors directly from stool samples in an enterotoxigenicMicrobiology spectrum · 2025Trial
- Performance evaluation of TaqMan Array Card real-time PCR for multi-pathogen detection in acute undifferentiated febrile illness.BMC infectious diseases · 2026Article
- Respiratory Illness and Diarrheal Disease Surveillance in U.S. Military Personnel Deployed to Southeast Asia for Military Exercises from 2023-2025.Tropical medicine and infectious disease · 2025Article
- GeoSentinel Analysis of Travelers' Diarrhea Antimicrobial Resistance Patterns.JAMA network open · 2025Article
- Prevalence and antimicrobial resistance ofOne health (Amsterdam, Netherlands) · 2025Review
- Understanding the etiology of diarrheal illness in Cambodia in a case-control study from 2020 to 2023.Gut pathogens · 2025Article
- Evidence of pathogens associated with travelers' diarrhea in Thailand: a systematic review.Tropical diseases, travel medicine and vaccines · 2025Article
- Emerging Strategies against Non-TyphoidalCurrent issues in molecular biology · 2024Review
- Article
- Seasonal variation of diarrhoeal pathogens among Guinea-Bissauan children under five years of age.PLoS neglected tropical diseases · 2023Article
- Travel-related gastrointestinal diseases: Assessment and management.Public health challenges · 2022Review
- Fast screening of enteropathogens in marine water samples.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022Article
- Weather variables as important clinical predictors of bacterial diarrhoea among international travellers.Journal of travel medicine · 2022Article
- Acute Viral Gastrointestinal (GI) Infections in the Tropics-A Role for Cartridge-Based Multiplex PCR Panels?Tropical medicine and infectious disease · 2022Review
- TaqMan Array Card testing of participant-collected stool smears to determine the pathogen-specific epidemiology of travellers' diarrhoea†.Journal of travel medicine · 2022Article
- Global epidemiology of campylobacteriosis and the impact of COVID-19.Frontiers in cellular and infection microbiology · 2022Review
- Etiology of acute febrile illnesses in Southern China: Findings from a two-year sentinel surveillance project, 2017-2019.PloS one · 2022Article
- Prevalence of diarrhoeal pathogens among children under five years of age with and without diarrhoea in Guinea-Bissau.PLoS neglected tropical diseases · 2021Article
- A Multisite Network Assessment of the Epidemiology and Etiology of Acquired Diarrhea among U.S. Military and Western Travelers (Global Travelers' Diarrhea Study): A Principal Role ofThe American journal of tropical medicine and hygiene · 2020Article
- Performance characteristics of a quantitative PCR assay on repository stool specimens and smeared filter-paper cards.BMC research notes · 2020Article
Corrections and comments
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Authors and funding
13 authors at 3 institutions in 2 countries.
Funding
Abstract
Background: Travelers' diarrhea (TD) is a common illness experienced by travelers from developed countries who visit developing countries. Recent questionnaire-based surveillance studies showed that approximately 6%-16% of travelers experienced TD while visiting Thailand; however, a majority of TD information was limited mainly to US military populations. Methods: A TD surveillance study was conducted at Bumrungrad International Hospital in 2012-2014 in Bangkok, Thailand. Enteropathogens were identified using conventional methods and the TaqMan® array card (TAC), which uses real-time polymerase chain reaction for the simultaneous detection of multiple pathogens. Analyses to determine pathogen-disease and symptoms association were performed to elucidate the clinical relevance of each enteropathogen. Results: TAC identified more pathogens per sample than conventional methods. Campylobacter spp. were the most prevalent, followed by the diarrheagenic Escherichia coli and norovirus GII. These agents had significant pathogen-disease associations as well as high attributable fractions among diarrheal cases. A wide range of pathogen loads for Campylobacter spp. was associated with TD, while heat-labile toxin enterotoxigenic Escherichia coli was associated with an increased pathogen load. Most cases were associated with inflammatory diarrhea, while Campylobacter spp. and Shigella spp. were associated with dysentery. Conclusions: A pan-molecular diagnostic method such as TAC produces quantifiable and comparable results of all tested pathogens, thereby reducing the variability associated with multiple conventional methods. This allows better determination of the clinical relevance of each diarrhea etiologic agent, as well as their geographical relevance in Thailand.
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