Evidence map›Paper›PMID 29351570›Full record

ArticleAnnals of oncology : official journal of the European Society for Medical Oncology2018

Joint adolescent-adult early phase clinical trials to improve access to new drugs for adolescents with cancer: proposals from the multi-stakeholder platform-ACCELERATE.

N Gaspar, L V Marshall, D Binner, R Herold, R Rousseau, P Blanc, R Capdeville, J Carleer, C Copland, Y Kerloeguen and 19 more

Abstract read
In one paragraph

Article in Annals of oncology : official journal of the European Society for Medical Oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  4. Menin Inhibition With Revumenib forJournal of clinical oncology : official journal of the American Society of Clinical Oncology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

N GasparDepartment of Oncology for Children and Adolescents, Gustave Roussy Cancer Campus, Villejuif, France. Electronic address: nathalie.gaspar@gustaveroussy.fr.
L V MarshallPaediatric and Adolescent Drug Development Team, Oak Centre for Children & Young People, The Royal Marsden Hospital & The Institute of Cancer Research, London, UK.
D BinnerCreate for Chloe and UK Representative for aPODD, European Medicines Agency, London, UK.
R HeroldProduct Development Scientific Support Department, European Medicines Agency, London, UK.
R RousseauGritstone Oncology, Inc., Emeryville, USA.
P BlancImagine for Margo, Fourqueux, France.
R CapdevilleNovartis AG, Basel, Switzerland.
J CarleerBelgium Federal Agency for Medicines and Health Products, EUROSTATION, Brussels, Belgium.
C CoplandCentre for English Language Teaching, University of York, York, UK.
Y KerloeguenPharmaceuticals Division, PDOA, Oncology, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
K NorgaPaediatric and Adolescent Drug Development Team, Oak Centre for Children & Young People, The Royal Marsden Hospital & The Institute of Cancer Research, London, UK; Universitair Ziekenhuis Antwerpen, Edegem, Belgium.
L PacaudNovartis AG, Basel, Switzerland.
M-A SevauxJeunes Solidarité Cancer, Paris, France.
C SpadoniaPODD Foundation, City Point, London, UK.
J SterbaPediatric Oncology Department, University Hospital Brno, School of Medicine Masaryk University Brno, Regional Centre for Applied Molecular Oncology, Masaryk Memorial Cancer Institute, ICRC Brno, St. Anna University Hospital Brno, Czech Republic.
F LigasProduct Development Scientific Support Department, European Medicines Agency, London, UK.
T TaubeBoehringer Ingelheim, Pharma GmbH&Co KG, TA Oncology, Biberach, Germany.
M Uttenreuther-FischerBoehringer Ingelheim, Pharma GmbH&Co KG, TA Oncology, Biberach, Germany.
S ChioatoRegulatory Strategy Oncology, Pfizer Italia, Milano, Italy.
M A O'ConnellRegulatory Strategy Oncology, Pfizer Italia, Milano, Italy.
B GeoergerDepartment of Oncology for Children and Adolescents, Gustave Roussy Cancer Campus, Villejuif, France.
J-Y BlayCentre Léon Bérard and University Claude Bernard Lyon 1, Lyon.
J C SoriaDrug Development Department (DITEP), Gustave Roussy, Villejuif and University Paris-Sud, Orsay, France.
S KayeAdult Drug Development Unit, The Royal Marsden Hospital and The Institute of Cancer Research, London, UK.
B WulffPaediatric Haematology/Oncology, Clinical Research/Paediatric Drug Development, University Childreńs Hospital III Hufelandstraße, Essen, Germany.
L BrugièresDepartment of Oncology for Children and Adolescents, Gustave Roussy Cancer Campus, Villejuif, France.
G VassalDepartment of Clinical Research, Gustave Roussy, Villejuif and Paris-Sud University, Le Kremlin-Bicêtre, France.
A D J PearsonPaediatric and Adolescent Drug Development Team, Oak Centre for Children & Young People, The Royal Marsden Hospital & The Institute of Cancer Research, London, UK.
Members of Working Group 1 of the Paediatric Platform of ACCELERATE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Clinical Trials as TopicDrug DevelopmentAdolescentAdultAntineoplastic AgentsFemaleHumansMaleNeoplasmsYoung AdultAntineoplastic Agents

Identifiers

PMID29351570
PMCPMC5889024

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.