Evidence map›Paper›PMID 29351559›Full record

ArticlePloS one2018

Characterisation of ictal and interictal states of epilepsy: A system dynamic approach of principal dynamic modes analysis.

Zabit Hameed, Saqib Saleem, Jawad Mirza, Muhammad Salman Mustafa, Qamar-Ul-Islam

Abstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Pannexin-1 Deficiency Decreases Epileptic Activity in Mice.International journal of molecular sciences · 2020
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zabit HameedDepartment of Electrical Engineering, Institute of Space Technology, Islamabad, Pakistan.
Saqib SaleemDepartment of Electrical Engineering, COMSATS Institute of Information Technology, Sahiwal, Pakistan.ORCID 0000-0002-3124-250X
Jawad MirzaDepartment of Electrical Engineering, COMSATS Institute of Information Technology, Islamabad, Pakistan.
Muhammad Salman MustafaDepartment of Mechanical Engineering, COMSATS Institute of Information Technology, Sahiwal, Pakistan.
Qamar-Ul-IslamDepartment of Electrical Engineering, Institute of Space Technology, Islamabad, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epilepsy is a brain disorder characterised by the recurrent and unpredictable interruptions of normal brain function, called epileptic seizures. The present study attempts to derive new diagnostic indices which may delineate between ictal and interictal states of epilepsy. To achieve this, the nonlinear modeling approach of global principal dynamic modes (PDMs) is adopted to examine the functional connectivity of the temporal and frontal lobes with the occipital brain segment using an ensemble of paediatric EEGs having the presence of epileptic seizure. The distinct spectral characteristics of global PDMs are found to be in line with the neural rhythms of brain dynamics. Moreover, we find that the linear trends of associated nonlinear functions (ANFs) associated with the 2nd and 4th global PDMs (representing delta, theta and alpha bands) of Fp1-F3 may differentiate between ictal and interictal states of epilepsy. These findings suggest that global PDMs and their associated ANFs may offer potential utility as diagnostic neural measures for ictal and interictal states of epilepsy.

Indexed as

ChildElectroencephalographyEpilepsyFrontal LobeHumansModels, NeurologicalNonlinear DynamicsSeizuresSystems AnalysisTemporal Lobe

Identifiers

PMID29351559
PMCPMC5774786

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.