Evidence map›Paper›PMID 29351471›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2018

When higher cholesterol is better: membrane cholesterol loss and endothelial Ca

John C Huetsch, Karthik Suresh, Larissa A Shimoda

Abstract readEditorialComment
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

John C HuetschDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins School of Medicine , Baltimore, Maryland.
Karthik SureshDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins School of Medicine , Baltimore, Maryland.
Larissa A ShimodaDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Johns Hopkins School of Medicine , Baltimore, Maryland.

Funding

Na+/H+ exchange in pulmonary hypertensionR01HL073859 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI SHIMODA, LARISSA A. · 2003 to 2020
$4.2M
The Calpain/CaMKII/NHE Signaling Pathway in PAHK08HL133475 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI HUETSCH, JOHN · 2016 to 2019
$687k
NHLBI NIH HHS K08 HL133475NHLBI NIH HHS R01 HL073859
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CalciumHypercholesterolemiaCholesterolEndotheliumHumansHypoxiaORAI1 ProteinCalciumCholesterolORAI1 ProteinORAI1 protein, human

Identifiers

PMID29351471
PMCPMC5966775

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.