Evidence map›Paper›PMID 29351465›Full record

ReviewAmerican journal of physiology. Heart and circulatory physiology2018

Emerging potential benefits of modulating NAD

Daniel S Matasic, Charles Brenner, Barry London

Open access · bronzeAbstract readReview
In one paragraph

Review in American journal of physiology. Heart and circulatory physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 62 citations in OpenAlex.

  1. Stretchable large-area transparent nanowire composite arrays for label-free multimodal interrogation of cardiac physiology.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Energy metabolism in health and diseases.Signal transduction and targeted therapy · 2025
    Review
  7. Control of NADThe EMBO journal · 2024
    Article
  8. Nicotinamide Riboside, a Promising Vitamin BMolecules (Basel, Switzerland) · 2023
    Review
  9. Time-of-day defines NADNature communications · 2023
    Article
  10. Review
  11. Article
  12. Circadian cardiac NADAmerican journal of physiology. Cell physiology · 2022
    Review
  13. Review
  14. Review
  15. Article
  16. Association between NADJournal of cellular and molecular medicine · 2022
    Article
  17. Review
  18. Review
  19. Article
  20. The Molecular Pathways of Pyroptosis in Atherosclerosis.Frontiers in cell and developmental biology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Daniel S MatasicDivision of Cardiovascular Medicine, Department of Medicine, University of Iowa , Iowa City, Iowa.ORCID 0000-0001-7010-6298
Charles BrennerAbboud Cardiovascular Research Center, University of Iowa , Iowa City, Iowa.
Barry LondonDivision of Cardiovascular Medicine, Department of Medicine, University of Iowa , Iowa City, Iowa.
University of Iowa · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007337 · NIGMS · UNIVERSITY OF IOWA · PI GEYER, PAMELA K., LENTZ, STEVEN R · 1985 to 2020
$15.9M
SUMOylation of Voltage-Gated Sodium Channels In Neuronal Hyperexcitability of Alzheimer’s DementiaR01HL115955 · NHLBI · UNIVERSITY OF IOWA · PI IRANI, KAIKOBAD J., LONDON, BARRY · 2013 to 2023
$5.4M
The SIRT1-Gpd1L-NAD+ interactome in regulation of the Neuronal Sodium Channel: Implications for Cognitive Impairment of Alzheimer’s DementiaR01HL147545 · NHLBI · UNIVERSITY OF IOWA · PI BRENNER, CHARLES M, IRANI, KAIKOBAD J. · 2019 to 2022
$2.9M
NHLBI NIH HHS R01 HL115955NHLBI NIH HHS R01 HL147545NIGMS NIH HHS T32 GM007337
6 · The paper itself

Abstract

Nicotinamide adenine dinucleotide (NAD

Indexed as

Dietary SupplementsAnimalsCardiovascular AgentsCardiovascular DiseasesEnergy MetabolismHumansMyocytes, CardiacNADOxidation-ReductionSignal TransductionCardiovascular AgentsNADcardiovascular diseasesischemia-reperfusionnicotinamide adenine dinucleotideoxidation-reduction (redox)

Identifiers

PMID29351465
PMCPMC5966770
OpenAlexW2777887312

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.