ReviewBrain sciences2018
Awake versus Asleep Deep Brain Stimulation Surgery: Technical Considerations and Critical Review of the Literature.
Review in Brain sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04361188 (UPDRS-III Comparisons of Deep Brain Stimulation for Parkinson's Disease Between Patients Receiving MAC and AAA Anesthesia), which is not on this map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
UPDRS-III Comparisons of Deep Brain Stimulation for Parkinson's Disease Between Patients Receiving MAC and AAA Anesthesia: a Randomized Controlled Trial
Who cites it
22 citing papers in PubMed, 62 citations in OpenAlex.
- Subthalamic versus Posterior Subthalamic Stimulation for Optimal Tremor Control in Parkinson's Disease.Stereotactic and functional neurosurgery · 2026Article
- A comparison of electrophysiological microrecording versus automatic MR-based segmentation to determine subthalamic nucleus boundaries.Acta neurochirurgica · 2025Article
- The role of intraoperative monitoring in target selection in deep brain stimulation: A single centre study.Clinical parkinsonism & related disorders · 2025Article
- Short-term 30-day adverse events following awake versus asleep deep brain stimulation for movement disorders: a nationwide registry-based study.Brain & spine · 2025Article
- Subthalamic Deep Brain Stimulation under General Anaesthesia for Parkinson's Disease: Institutional Experience and Outcomes.Stereotactic and functional neurosurgery · 2025Article
- Prediction of pyramidal tract side effect threshold by intra-operative electromyography in subthalamic nucleus deep brain stimulation for patients with Parkinson's disease under general anaesthesia.Frontiers in surgery · 2024Article
- Intraoperative physiology augments atlas-based data in awake deep brain stimulation.Journal of neurology, neurosurgery, and psychiatry · 2023Article
- Two-photon microendoscope for label-free imaging in stereotactic neurosurgery.Biomedical optics express · 2023Article
- Association of clinical outcomes and connectivity in awake versus asleep deep brain stimulation for Parkinson disease.Journal of neurosurgery · 2023Article
- [Towards a positive physiological definition of the deep brain nuclei in humans].Revista de neurologia · 2022Article
- Anesthesia for deep brain stimulation system implantation: adapted protocol for awake and asleep surgery using microelectrode recordings.Acta neurochirurgica · 2022Article
- Surgical Strategy for Directional Deep Brain Stimulation.Neurologia medico-chirurgica · 2022Article
- Indication and eligibility of glioma patients for awake surgery: A scoping review by a multidisciplinary perspective.Frontiers in oncology · 2022Article
- Impact of Procedural Sedation on the Clinical Outcome of Microelectrode Recording Guided Deep Brain Stimulation in Patients with Parkinson's Disease.Journal of clinical medicine · 2021Article
- Capturing Initial Understanding and Impressions of Surgical Therapy for Parkinson's Disease.Frontiers in neurology · 2021Article
- Bilateral Subthalamic Nucleus Deep Brain Stimulation under General Anesthesia: Literature Review and Single Center Experience.Journal of clinical medicine · 2020Review
- Can We Put Aside Microelectrode Recordings in Deep Brain Stimulation Surgery?Brain sciences · 2020Article
- Deep brain stimulation and other surgical modalities for the management of essential tremor.Expert review of medical devices · 2020Review
- A comparative study of asleep and awake deep brain stimulation robot-assisted surgery for Parkinson's disease.NPJ Parkinson's disease · 2020Article
- Neural Circuit and Clinical Insights from Intraoperative Recordings During Deep Brain Stimulation Surgery.Brain sciences · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Advancements in neuroimaging have led to a trend toward direct, image-based targeting under general anesthesia without the use of microelectrode recording (MER) or intraoperative test stimulation, also referred to as "asleep" deep brain stimulation (DBS) surgery. Asleep DBS, utilizing imaging in the form of intraoperative computed tomography (iCT) or magnetic resonance imaging (iMRI), has demonstrated reliable targeting accuracy of DBS leads implanted within the globus pallidus and subthalamic nucleus while also improving clinical outcomes in patients with Parkinson's disease. In lieu, of randomized control trials, retrospective comparisons between asleep and awake DBS with MER have shown similar short-term efficacy with the potential for decreased complications in asleep cohorts. In lieu of long-term outcome data, awake DBS using MER must demonstrate more durable outcomes with fewer stimulation-induced side effects and lead revisions in order for its use to remain justifiable; although patient-specific factors may also be used to guide the decision regarding which technique may be most appropriate and tolerable to the patient.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.