Evidence map›Paper›PMID 29350999›Full record

ReviewAmerican journal of physiology. Heart and circulatory physiology2018

Sex differences in abdominal aortic aneurysms.

Austin C Boese, Lin Chang, Ke-Jie Yin, Y Eugene Chen, Jean-Pyo Lee, Milton H Hamblin

Open access · bronzeAbstract readReview
In one paragraph

Review in American journal of physiology. Heart and circulatory physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 62 citations in OpenAlex.

  1. Review
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  17. Unleashing PD-1: a duel of immunity in aortic aneurysm formation.The Journal of clinical investigation · 2024
    Article
  18. Review
  19. A New AutosomalArteriosclerosis, thrombosis, and vascular biology · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Austin C BoeseDepartment of Pharmacology, Tulane University School of Medicine , New Orleans, Louisiana.
Lin ChangCenter for Advanced Models for Translational Sciences and Therapeutics, Department of Internal Medicine, University of Michigan , Ann Arbor, Michigan.
Ke-Jie YinDepartment of Neurology, University of Pittsburgh School of Medicine , Pittsburgh, Pennsylvania.
Y Eugene ChenCenter for Advanced Models for Translational Sciences and Therapeutics, Department of Internal Medicine, University of Michigan , Ann Arbor, Michigan.
Jean-Pyo LeeDepartment of Physiology, Tulane University School of Medicine , New Orleans, Louisiana.
Milton H HamblinDepartment of Pharmacology, Tulane University School of Medicine , New Orleans, Louisiana.
Tulane University · USUniversity of Michigan–Ann Arbor · USCenter for Neuroscience and Regenerative Medicine · USUniversity of Pittsburgh · US

Funding

Tulane Building Interdisciplinary Research Careers in Women's Health (BIRCWH)K12HD043451 · NICHD · TULANE UNIVERSITY OF LOUISIANA · PI KROUSEL-WOOD, MARIE · 2002 to 2023
$9.9M
NICHD NIH HHS K12 HD043451
6 · The paper itself

Abstract

Abdominal aortic aneurysm (AAA) is a vascular disorder with a high case fatality rate in the instance of rupture. AAA is a multifactorial disease, and the etiology is still not fully understood. AAA is more likely to occur in men, but women have a greater risk of rupture and worse prognosis. Women are reportedly protected against AAA possibly by premenopausal levels of estrogen and are, on average, diagnosed at older ages than men. Here, we review the present body of research on AAA pathophysiology in humans, animal models, and cultured cells, with an emphasis on sex differences and sex steroid hormone signaling.

Indexed as

Health Status DisparitiesAge of OnsetAnimalsAorta, AbdominalAortic Aneurysm, AbdominalBiomechanical PhenomenaFemaleGonadal Steroid HormonesHemodynamicsHumansMalePrognosisProtective FactorsRisk FactorsSex FactorsSignal TransductionGonadal Steroid Hormonesabdominal aortic aneurysmandrogen signalingestrogen signalingsex differencessex steroid hormones

Identifiers

PMID29350999
PMCPMC6032079
OpenAlexW2782691119

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.