Evidence map›Paper›PMID 29350650›Full record

ArticleActa bio-medica : Atenei Parmensis2018

Clinical and instrumental assessment of herniated discs after nucleoplasty: a preliminary study.

Alessandro Liguori, Federica Galli, Martina Gurgitano, Anna Borelli, Marco Pandolfi, Ferdinando Caranci, Alberto M Magenta Biasina, Giovanni G M Pompili, Claudia L Piccolo, Vittorio Miele and 2 more

Open access · greenAbstract read
In one paragraph

Article in Acta bio-medica : Atenei Parmensis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Efficacy of Single Level Versus Double Levels Surgery of Percutaneous Disc Nucleoplasty (PDN) Approach in Treating Lumbar Disc Herniation.Medical science monitor : international medical journal of experimental and clinical research · 2021
    Article
  4. Observational
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Alessandro Liguori. alessandroliguori.medicina@gmail.com.
Federica Galli
Martina Gurgitano
Anna Borelli
Marco Pandolfi
Ferdinando Caranci
Alberto M Magenta Biasina
Giovanni G M Pompili
Claudia L Piccolo
Vittorio Miele
Carlo Masciocchi
Giampaolo Carrafiello
Azienda Sanitaria Locale Alessandria · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimThe therapy for low back pain boasts different approaches; one of these is nucleoplasty. We wanted to assess the effectiveness of nucleoplasty both by clinical response both by MR imaging evaluation, including even extrusions larger than one third of the spinal canal.

methodsFifty-seven patients were treated with nucleoplasty in our hospital, 11 of these patients accepted both clinical and MRI evaluation after six months from treatment. The clinical evaluation was performed with Visual Analogue Scale (VAS) of pain, scored before and after the procedure. MRI evaluation consisted of analysing some imaging parameters of disc protrusions before and after the treatment.

resultsIn 10 out of 11 (91%) patients, VAS was reduced and only 1 out of 11 (9%) had the same pain after procedure. The mean of decrease of VAS score was 64%. In our population 8/11 (72%) patients had a herniation larger than 1/3 of the sagittal diameter of spinal canal and 100% of them had an improvement with a mean VAS reduction value of 75%. With MRI evaluation, the mean percentage of expulsion before and after treatment was respectively 40% and 34%. The expulsion decreased in 7/13 discs, remained equal in 4/13, and increased in 2/13 discs. Among the 9 larger protrusions, 3 didn't change, 6 reduced with a decrease mean value of 13%. Other MRI parameters didn't change significantly.

conclusionsOur preliminary experience supports the success of coblation on pain relief, aiming to show progressively that this treatment is suitable even in case of great extrusions, which are generally treated only with surgical approach. It's not clear the usefulness of MRI control yet, even if in most of cases we could have found a certain reduction of expulsion degree.

Indexed as

ElectrocoagulationRadiofrequency AblationAdultAgedDecompression, SurgicalFemaleHumansIntervertebral Disc DisplacementLow Back PainLumbar VertebraeMagnetic Resonance ImagingMaleMiddle AgedVisual Analog Scaledisc protrusion, nucleoplasty, Visual Analog Scale (VAS), Magnetic Resonance Imaging (MRI)

Identifiers

PMID29350650
PMCPMC6179072
OpenAlexW2800845089

What OpenQuestion holds

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LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.