ReviewActa bio-medica : Atenei Parmensis2018
Magnetic Resonance Imaging correlates of benign and malignant alterations of the spinal bone marrow.
Review in Acta bio-medica : Atenei Parmensis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Artificial Intelligence for Detection and Characterisation of Bone Metastases on MRI: A Scoping Review.Cancers · 2026Review
- ISSLS Prize in Bioengineering Science 2026: Hidden in Plain Sight: Machine Learning-Assisted MRI Reveals Novel Vertebral Body Biomarkers of Chronic Low Back Pain in Humans.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Bone marrow metastasis from gastric cancer: A case report.Oncology letters · 2026Article
- AI for Lesion Detection in Musculoskeletal Radiology.Journal of the Korean Society of Radiology · 2025Review
- Chronic headache and obstructive hydrocephalus: A case of pilocytic astrocytoma in the third ventricle with detailed radiological and histopathological findings.Radiology case reports · 2025Article
- The Never Ending Story-What Are the Differentiable Magnetic Resonance Imaging Characteristics Between Pyogenic and Mycobacterial Thoracolumbar Infections?Journal of clinical medicine · 2025Article
- MRI features of spinal chronic recurrent multifocal osteomyelitis/chronic non-bacterial osteomyelitis in children.Pediatric radiology · 2023Article
- Added value of coronal-T1W sequence to the lumbar MR imaging protocol for low back pain.Biomedica : revista del Instituto Nacional de Salud · 2022Article
- Dose-volume parameters of MRI-based active bone marrow predict hematologic toxicity of chemoradiotherapy for rectal cancer.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2020Article
- Bone marrow reconversion mimicking pelvis metastases in a patient with rectal cancer: a pitfall on magnetic resonance images.Quantitative imaging in medicine and surgery · 2018Article
- Clinical impact of coronal-STIR sequence in a routine lumbar spine MR imaging protocol to investigate low back pain.Medicine · 2018Observational
- Dose-Volume Parameters of Spared Magnetic Resonance Imaging-Defined Active Bone Marrow Predict Hematologic Toxicity in Pelvic Malignancies Patients Undergoing Radiotherapy: A Cohort Study.Technology in cancer research & treatmentArticle
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and aim of the workBone marrow (BM) abnormalities in the spine are a common, sometimes unexpected, finding on Magnetic Resonance Imaging (MRI), which is the most sensitive imaging modality to evaluate the marrow, and their interpretation can be difficult for the unexperienced radiologist. In this review, the MRI appearance of normal age-related BM changes, as well as the imaging features of benign and malignant diseases, are presented. DISCUSSION: A large variety of BM signal alterations has been identified and described, including normal variants, BM reconversion, degenerative changes, infections, spondyloarthritis and osteonecrosis, trauma, neoplastic lesions (both primary or metastatic), post-radiation and chemotherapy sequelae.
conclusionsKnowledge of normal age-related BM appearance, normal variants and patterns of involvement in focal and diffuse bone diseases is essential, together with clinical and laboratory data, to narrow the list of the possible differential diagnoses. The radiologist should be familiar with these signal changes, as they can sometimes be discovered incidentally. In this context, it is equally important not to attribute pathological significance to benign alterations and to promptly detect signs of malignant diseases.
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