Evidence map›Paper›PMID 29350584›Full record

ReviewPathogens and global health2017

Developing standard operating procedures for gene drive research in disease vector mosquitoes.

Zach N Adelman, David Pledger, Kevin M Myles

Abstract readReview
In one paragraph

Review in Pathogens and global health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. A Cross-Sectional Survey of Biosafety Professionals Regarding Genetically Modified Insects.Applied biosafety : journal of the American Biological Safety Association · 2020
    Article
  7. Review
  8. Article
  9. How to handle gene drives in arthropods?Pathogens and global health · 2017
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Zach N Adelmana Department of Entomology , Texas A&M University , College Station , TX , USA.
David Pledgera Department of Entomology , Texas A&M University , College Station , TX , USA.
Kevin M Mylesa Department of Entomology , Texas A&M University , College Station , TX , USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Numerous arthropod species represent potential targets for gene-drive-based population suppression or replacement, including those that transmit diseases, damage crops, or act as deleterious invasive species. Containment measures for gene drive research in arthropods have been discussed in the literature, but the importance of developing safe and effective standard operating procedures (SOPs) for these types of experiments has not been adequately addressed. Concisely written SOPs link safe work practices, containment measures, institutional training, and research-specific protocols. Here we discuss information to be considered by principal investigators, biosafety officers, and institutional biosafety committees as they work together to develop SOPs for experiments involving gene drive in arthropods, and describe various courses of action that can be used to maintain the effectiveness of SOPs through evaluation and revision. The information provided herein will be especially useful to investigators and regulatory personnel who may lack extensive experience working with arthropods under containment conditions.

Indexed as

AnimalsEntomologyGene Drive TechnologyHumansMosquito ControlMosquito VectorsarthropodbiosafetycontainmentGene driveinsectmosquitoSOPstandard operating procedures

Identifiers

PMID29350584
PMCPMC6066849

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.