Evidence map›Paper›PMID 29350547›Full record

ReviewDNA and cell biology2018

Regulation of Autophagy by Hepatitis C Virus for Its Replication.

Linya Wang, Jing-Hsiung James Ou

Abstract readReview
In one paragraph

Review in DNA and cell biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 27 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Autophagy in liver diseases.World journal of hepatology · 2021
    Review
  8. Hepatitis C Virus Replication.Cold Spring Harbor perspectives in medicine · 2020
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Dual NDP52 Function in Persistent CSFV Infection.Frontiers in microbiology · 2019
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Linya WangDepartment of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California , Los Angeles, California.
Jing-Hsiung James OuDepartment of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California , Los Angeles, California.
University of Southern California · US

Funding

Hepatitis C virus and autophagic responseR01DK094652 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI OU, J.-H. JAMES · 2011 to 2020
$3.2M
NIDDK NIH HHS R01 DK094652
6 · The paper itself

Abstract

Macroautophagy, hereafter autophagy, is a catabolic process that is important for maintaining cellular homeostasis. It can also be used by cells to remove intracellular microbial pathogens. However, the studies on hepatitis C virus (HCV) in recent years indicated that this virus could regulate this cellular pathway and use it to enhance its replication. HCV could temporally control the autophagic flux and use the autophagic membranes for the assembly of its RNA replication complex. In this report, we will discuss the biogenesis of autophagosomes induced by HCV and how HCV uses this autophagic pathway for its RNA replication.

Indexed as

AutophagosomesAutophagyDNA ReplicationHepacivirusHumansPhagosomesRNA, ViralVirus ReplicationRNA, Viralautophagosomesautophagyhepatitis C virushomotypic fusionphagophores

Identifiers

PMID29350547
PMCPMC5963595
OpenAlexW2791644447

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.