Evidence map›Paper›PMID 29350456›Full record

ArticlePediatric blood & cancer2018

A prospective study of family predictors of health-related quality of life in pediatric brain tumor survivors.

Lauren F Quast, Peter C Phillips, Yimei Li, Anne E Kazak, Lamia P Barakat, Matthew C Hocking

Abstract read
In one paragraph

Article in Pediatric blood & cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lauren F QuastThe Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Peter C PhillipsDivision of Oncology, The Children's Hospital of Philadelphia and the Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Yimei LiDivision of Oncology, The Children's Hospital of Philadelphia and the Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Anne E KazakNemours Children's Health System and Sidney Kimmel School of Medicine, Thomas Jefferson University, Wilmington, Delaware.
Lamia P BarakatDivision of Oncology, The Children's Hospital of Philadelphia and the Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Matthew C HockingDivision of Oncology, The Children's Hospital of Philadelphia and the Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.ORCID 0000-0002-1368-0856

Funding

UNIVERSITY OF PENNSYLVANIA CAN CTR SUPPORT GRANTP30CA016520 · NCI · UNIVERSITY OF PENNSYLVANIA · PI Robert H. Vonderheide · 1985 to 2026
$222.3M
The Intellectual and Developmental Disabilities Research Center at CHOP/PennU54HD086984 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI ROBERTS, TIMOTHY P · 2016 to 2020
$6.3M
A Prospective Study of Social Competence in Pediatric Brain Tumor SurvivorsK07CA178100 · NCI · CHILDREN'S HOSP OF PHILADELPHIA · PI HOCKING, MATTHEW C. · 2013 to 2017
$639k
Neurocognitive and Family Functioning at End of Therapy in Pediatric Brain TumorR03CA162970 · NCI · CHILDREN'S HOSP OF PHILADELPHIA · PI HOCKING, MATTHEW C. · 2012 to 2013
$162k
NCI NIH HHS K07 CA178100NCI NIH HHS P30 CA016520NCI NIH HHS R03 CA162970NICHD NIH HHS U54 HD086984
6 · The paper itself

Abstract

backgroundThe objective of this study was to examine prospectively the associations between family functioning at the end of tumor-directed treatment and the health-related quality of life (HRQL) of pediatric brain tumor survivors (PBTSs) approximately 9 months later. PROCEDURE: Thirty-five PBTS (age 6-16 years) and their mothers completed measures of family functioning and survivor HRQL within 5 months of completing tumor-directed therapy (baseline) and again approximately 9 months later (follow-up).

resultsSurvivor-rated general family functioning at baseline significantly predicted mother proxy- and self-reported survivor HRQL at follow-up when controlling for survivor HRQL at baseline and relevant demographic and treatment-related variables.

conclusionsFamily functioning is a key factor contributing to survivor HRQL and should be screened throughout the course of tumor-directed treatment. Psychosocial interventions directed toward improving general family functioning may improve survivor well-being following the completion of treatment.

Indexed as

Family RelationsQuality of LifeAdolescentBrain NeoplasmsChildFemaleFollow-Up StudiesHealth StatusHumansMalePrognosisProspective StudiesSurvival RateSurvivorsbrain tumorfamily functioningquality of life

Identifiers

PMID29350456
PMCPMC5911210

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.