Evidence map›Paper›PMID 29350437›Full record

ArticleNMR in biomedicine2018

Diffusion tensor imaging MRI of sickle cell kidney disease: initial results and comparison with iron deposition.

Shannon B Donnola, Connie M Piccone, Lan Lu, Joshua Batesole, Jane Little, Katherine M Dell, Chris A Flask

Open access · greenAbstract readComparative Study
In one paragraph

Article in NMR in biomedicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Diffusion tensor imaging of the healthy feline kidney.Journal of feline medicine and surgery · 2026
    Article
  5. Article
  6. Review
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Shannon B DonnolaDepartment of Radiology, Case Western Reserve University, Cleveland, OH, USA.ORCID 0000-0002-7489-3011
Connie M PicconeDepartment of Pediatrics, Case Western Reserve University, Cleveland, OH, USA.
Lan LuDepartment of Radiology, Case Western Reserve University, Cleveland, OH, USA.
Joshua BatesoleDepartment of Radiology, Case Western Reserve University, Cleveland, OH, USA.
Jane LittleDepartment of Medicine, Case Western Reserve University, Cleveland, OH, USA.
Katherine M DellDepartment of Pediatrics, Case Western Reserve University, Cleveland, OH, USA.
Chris A FlaskDepartment of Radiology, Case Western Reserve University, Cleveland, OH, USA.
Case Western Reserve University · USMetroHealth · USRainbow Babies & Children's Hospital · USUniversity Hospitals of Cleveland · US

Funding

TUMOR METABOLISM PROGRAMP30CA043703 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI Amar Desai · 1987 to 2026
$142.3M
Clinical and Translational Science Collaborative of ClevelandUL1TR000439 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI KONSTAN, MICHAEL W. · 2012 to 2016
$50.0M
Clinical and Translational Science Collaborative of ClevelandTL1TR000441 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI KONSTAN, MICHAEL W. · 2012 to 2016
$2.8M
NCATS NIH HHS TL1 TR000441NCATS NIH HHS UL1 TR000439NCI NIH HHS P30 CA043703NIH HHS P30 CA43703
6 · The paper itself

Abstract

Chronic kidney disease (CKD) occurs in over one-third of patients with sickle cell disease (SCD) and can progress to end-stage renal disease. Unfortunately, current clinical assessments of kidney function are insensitive to early-stage CKD. Previous studies have shown that diffusion magnetic resonance imaging (MRI) can sensitively detect regional renal microstructural changes associated with early-stage CKD. However, previous MRI studies in patients with SCD have been largely limited to the detection of renal iron deposition assessed by T

Indexed as

Diffusion Tensor ImagingAdolescentAdultAnemia, Sickle CellAnisotropyAspartate AminotransferasesChildFemaleHumansIronKidney DiseasesMaleYoung AdultAspartate AminotransferasesIrondiffusionkidneymagnetic resonance imagingrelaxometrysickle cell disease

Identifiers

PMID29350437
PMCPMC5822685
OpenAlexW2789606744

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.