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ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2018

Measurement invariance and general population reference values of the PROMIS Profile 29 in the UK, France, and Germany.

Felix Fischer, Chris Gibbons, Joël Coste, Jose M Valderas, Matthias Rose, Alain Leplège

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05122793 ("HerzCheck" - Erkennung Und Prävention Einer Frühen Herzinsuffizienz Mittels Telemedizinischer Verfahren in Strukturschwachen Regionen), which is not on this map. Cited by 54 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05122793 naactive not recruitingnot on this mapstarted 2021, after this paper: background citation

"HerzCheck" - Erkennung Und Prävention Einer Frühen Herzinsuffizienz Mittels Telemedizinischer Verfahren in Strukturschwachen Regionen

TypeinterventionalSponsorGerman Heart InstituteRan2021 to 2034Enrolled4,509ConditionsHeart Failure with Preserved Ejection FractionArmsPrevention offer
3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Utility of the Patient-Reported Outcomes Measurement Information System (PROMIS) to measure primary health outcomes in cancer patients: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Pooled it
  2. Using a measurement type-independent metric to compare patterns of determinants between patient-reported versus performance-based physical function in hemodialysis patients.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
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  11. Reference values for the PROMISBMC public health · 2025
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  13. Psychometric properties, and cultural appropriateness, of patient reported outcome measures for use in primary healthcare: a scoping review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
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  15. Ashwagandha (BMJ open · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Felix FischerDepartment of Psychosomatic Medicine, Center for Internal Medicine and Dermatology, Charité - Universitätsmedizin Berlin, Corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany. felix.fischer@charite.de.ORCID 0000-0002-9693-6676
Chris GibbonsThe Psychometrics Centre, Judge Business School, University of Cambridge, Cambridge, UK.
Joël CosteAPEMAC, EA 4360, Paris Descartes University, Paris, France.
Jose M ValderasHealth Services & Policy Research Group, University of Exeter, Exeter, UK.
Matthias RoseDepartment of Psychosomatic Medicine, Center for Internal Medicine and Dermatology, Charité - Universitätsmedizin Berlin, Corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Charitéplatz 1, 10117, Berlin, Germany.
Alain LeplègeAPEMAC, EA 4360, Paris Descartes University, Paris, France.

Funding

Centre Virchow Villerme NADepartment of Health CDF-2017-10-019
6 · The paper itself

Abstract

purposeComparability of patient-reported outcome measures over different languages is essential to allow cross-national research. We investigate the comparability of the PROMIS Profile 29, a generic health-related quality of life measure, in general population samples in the UK, France, and Germany and present general population reference values.

methodsA web-based survey was simultaneously conducted in the UK (n = 1509), France (1501), and Germany (1502). Along with the PROMIS Profile 29, we collected sociodemographic information as well as the EQ-5D. We tested measurement invariance by means of multigroup confirmatory factor analysis (CFA). Differences in the health-related quality of life between countries were modeled by linear regression analysis. We present general population reference data for the included PROMIS domains utilizing plausible value imputation and quantile regression.

resultsMultigroup CFA of the PROMIS Profile 29 showed that factor means are insensitive to potential measurement bias except in one item. We observed significant differences in patient-reported health between countries, which could be partially explained by the differences in overall ratings of health. The physical function and pain interference scales showed considerable floor effects in the normal population in all countries.

conclusionsScores derived from the PROMIS Profile 29 are largely comparable across the UK, France, and Germany. Due to the use of plausible value imputation, the presented general population reference values can be compared to data collected with other PROMIS short forms or computer-adaptive tests.

Indexed as

Factor Analysis, StatisticalPatient Reported Outcome MeasuresAdolescentAdultAgedFemaleFranceGermanyHumansMaleMiddle AgedQuality of LifeReference ValuesSelf ReportSurveys and QuestionnairesUnited KingdomCross-cultural equivalenceGeneral population referenceItem response theoryPatient-reported outcomesPlausible value imputationSelf-reported health

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.