SynthesisClinical rheumatology2018
Role of dual-energy CT in the diagnosis and follow-up of gout: systematic analysis of the literature.
Synthesis in Clinical rheumatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 35 citations in OpenAlex.
- Review
- The association between crystallopathy and postoperative complications following total hip and knee arthroplasty: a systematic review and meta-analysis.Annals of medicine and surgery (2012) · 2026Article
- Article
- Endoscopic management of lumbar spinal tophaceous gout: six cases treated with percutaneous transforaminal (PTED) and interlaminar (PIED) discectomy and a literature review.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Review
- Material decomposition approaches for monosodium urate (MSU) quantification in gouty arthritis: a (bio)phantom study.European radiology experimental · 2024Article
- Computed tomography-current status and future directions for arthritis imaging.Therapeutic advances in musculoskeletal disease · 2024Review
- Costochondral gout.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2022Article
- The role of dual energy computed tomography in the differentiation of acute gout flares and acute calcium pyrophosphate crystal arthritis.Clinical rheumatology · 2022Article
- A glance into the future of gout.Therapeutic advances in musculoskeletal disease · 2022Review
- Reliability of knee joint sonography in the evaluation of gouty arthritis.Journal of ultrasonography · 2021Article
- A novel parameter derived from post-processing procedure of dual energy CT for identification of gout.Scientific reports · 2021Article
- What Has Dual Energy CT Taught Us About Gout?Current rheumatology reports · 2021Review
- [CT spectral curve in differentiating spinal tumor metastasis and infections].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2020Article
- Seasonal variation in the internet searches for gout: an ecological study.Clinical rheumatology · 2019Observational
- The Differentiation of Soft Tissue Infiltration and Surrounding Edema in an Animal Model of Malignant Bone Tumor: Evaluation by Dual-Energy CT.Technology in cancer research & treatment · 2019Article
- Ultra-low-dose CT detects synovitis in patients with suspected rheumatoid arthritis.Annals of the rheumatic diseases · 2019Article
- Current status of ultrasound and dual-energy computed tomography in the evaluation of gout.Rheumatology international · 2018Review
- Federated learning-based virtual dual-energy CT generation from single-energy CT for gout detection.Digital healthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this systematic review was to determine the potential role of dual-energy CT in the diagnosis and follow-up of gout with regard to the Outcome Measures in Rheumatology (OMERACT) filter. A systematic analysis of the literature was conducted using the MEDLINE and Cochrane databases and published abstracts of international congresses, according to the criteria of the OMERACT filter: feasibility, reproducibility, validity versus laboratory (serum urate, MSU synovial fluid aspirate) and other imaging modalities for gout, and its sensitivity to change in patients on urate lowering therapy (ULT). Thirty-two articles were found representing a total of 1502 patients. The data on feasibility showed that the examination took little time and involved low levels of radiation but had current limited availability. Intra- and inter-observer reproducibility was excellent, with intra-class correlation coefficients > 0.9. Validity in comparison with polarized-light microscopy showed good sensitivity and specificity (> 80%). The diagnostic performance was better than that of radiography and conventional CT-scan and at least equivalent to that of ultrasonography. The sensitivity to change varied with effect sizes from 0.05 (low) to 1.24 (high) for decrease in the tophus volume following different ULT in gout patients. Dual-energy CT-scan is a reproducible and accurate imaging modality for the diagnosis of gout, particularly for tophaceous gout (intra- or extra-articular). It can become a second-line imaging modality of choice in cases of diagnostic doubt, such as ultrasonography. Its role remains uncertain in the follow-up of gout patients treated with ULT and needs further clarification.
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