SynthesisJournal of thrombosis and thrombolysis2018
Do telehealth interventions improve oral anticoagulation management? A systematic review and meta-analysis.
Synthesis in Journal of thrombosis and thrombolysis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Telemedicine-Based Management of Oral Anticoagulation Therapy: Systematic Review and Meta-analysis.Journal of medical Internet research · 2023Pooled it
- Telemedicine in the OECD: An umbrella review of clinical and cost-effectiveness, patient experience and implementation.PloS one · 2020Pooled it
- Guideline of the Brazilian Society of Cardiology on Telemedicine in Cardiology - 2019.Arquivos brasileiros de cardiologia · 2019Guideline
- Coordination of oral anticoagulant care at hospital discharge (COACHeD): pilot randomised controlled trial.BMJ open · 2024Trial
- The Effectiveness of Digital Therapeutics Intervention in Oral Anticoagulation Management: A Systematic Review and Meta-analysis.Mayo Clinic proceedings. Digital health · 2026Article
- Effect of internet plus nursing mode telehealth intervention on warfarin management in atrial fibrillation patients.Frontiers in cardiovascular medicine · 2026Article
- A comprehensive global review on pharmacist-led strategies to support medication therapy in hypertensive patients.Journal of human hypertension · 2025Review
- Temporary Telemedicine Policy and Chronic Disease Management in South Korea: Retrospective Analysis Using National Claims Data.JMIR public health and surveillance · 2024Article
- The Value of Anticoagulation Management Combining Telemedicine and Self-Testing in Cardiovascular Diseases: A Meta-Analysis of Randomized Controlled Trials.Therapeutics and clinical risk management · 2023Article
- Coordination of Oral Anticoagulant Care at Hospital Discharge (COACHeD): protocol for a pilot randomised controlled trial.Pilot and feasibility studies · 2022Article
- Defining Telehealth for Research, Implementation, and Equity.Journal of medical Internet research · 2022Article
- Review
- Effectiveness of Telephone Monitoring in Primary Care to Detect Pneumonia and Associated Risk Factors in Patients with SARS-CoV-2.Healthcare (Basel, Switzerland) · 2021Article
- Review of Systematic Reviews in the Field of Telemedicine.Medical journal of the Islamic Republic of Iran · 2021Article
- Telemedicine for COVID-19.Revista clinica espanola · 2020Article
- [Telemedicine for COVID-19].Revista clinica espanola · 2020Article
- Management of anticoagulant therapy using a portable point-of-care international normalized ratio device and social networking service in a patient with a left ventricular assist device.Journal of cardiology cases · 2020Article
- Barriers and facilitators to optimal oral anticoagulant management: a scoping review.Journal of thrombosis and thrombolysis · 2020Article
- Technology-Based Interventions in Oral Anticoagulation Management: Meta-Analysis of Randomized Controlled Trials.Journal of medical Internet research · 2020Review
- Atrial fibrillation care in rural communities: a mixed methods study of physician and patient perspectives.BMC family practice · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
The benefits and harms of telehealth interventions compared to usual care for oral anticoagulation management are unclear. A systematic review and meta-analysis was conducted to assess their impact on clinically important outcomes. A search was conducted through MEDLINE, EMBASE and CENTRAL databases, and the retrieved citations were independently screened and extracted by two review authors. Cochrane Collaboration-recommended tools were used to assess for risk of bias. Co-primary outcomes were major bleeding and major thromboembolic events. Of 2145 retrieved citations, 7 were included for qualitative synthesis (1 randomized controlled trial, 1 prospective cohort and 5 retrospective cohorts). None addressed direct oral anticoagulants. Telehealth interventions were mainly consisted of telephone visits by clinicians, pharmacists and specialists. Meta-analysis of 3 studies (n = 6955) showed significant improvements in the telehealth group for major thromboembolic events (RR 0.43, 95% CI 0.25-0.74, p = 0.002), but no significant difference for major bleeding events (RR 0.83, 95% CI 0.52-1.33, p = 0.44). There was no significant difference in any of the secondary outcomes. The overall GRADE quality of evidence was rated very low due to high risk of bias and low precision. Based on very low quality evidence, telehealth interventions may lower the risk of major thromboembolic events, but not other clinically important outcomes. A high quality study is likely to strongly influence these results. High quality randomized trials are recommended to better assess the benefits and harms of telehealth interventions for anticoagulation management.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.