Evidence map›Paper›PMID 29350299›Full record

ArticleChemistry Central journal2018

Mutagenicity, cytotoxic and antioxidant activities of Ricinus communis different parts.

Mazhar Abbas, Abid Ali, Muhammad Arshad, Asia Atta, Zahed Mehmood, Imtiaz Mahmood Tahir, Munawar Iqbal

Open access · goldAbstract read
In one paragraph

Article in Chemistry Central journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 52 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Phytogenic Silver Nanoparticles Derived fromBioengineering (Basel, Switzerland) · 2025
    Article
  6. A perspective review on factors that influence mutagenicity in medicinal plants and their health implications.Toxicological sciences : an official journal of the Society of Toxicology · 2025
    Review
  7. Phytochemical, Cytotoxic, and Antimicrobial Evaluation ofEvidence-based complementary and alternative medicine : eCAM · 2022
    Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Mazhar AbbasDepartment of Basic Sciences, Section Biochemistry, College of Veterinary and Animal Sciences, Jhang Campus, Jhang, 35200, Pakistan.
Abid AliCollege of Allied Health Professional, Directorate of Medical Science, Govt. College University, Faisalabad, Pakistan.
Muhammad ArshadDepartment of Basic Sciences, Section Biochemistry, College of Veterinary and Animal Sciences, Jhang Campus, Jhang, 35200, Pakistan.
Asia AttaDepartment of Biochemistry, Bahauddin Zakariya University, Multan, 60800, Pakistan.
Zahed MehmoodDepartment of Applied Chemistry and Biochemistry, Govt. College University, Faisalabad, Pakistan.
Imtiaz Mahmood TahirCollege of Allied Health Professional, Directorate of Medical Science, Govt. College University, Faisalabad, Pakistan.
Munawar IqbalDepartment of Chemistry, The University of Lahore, Lahore, Pakistan. bosalvee@yahoo.com.
Government College University, Faisalabad · PKUniversity of Veterinary and Animal Sciences · PKBahauddin Zakariya University · PKUniversity of Lahore · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ricinus communis (castor plant) is a potent medicinal plant, which is commonly used in the treatment of various ailments. The present study was conducted to appraise the cytotoxicity and mutagenicity of R. communis along with antioxidant and antimicrobial activities. Cytotoxicity was evaluated by hemolytic and brine shrimp assays, whereas Ames test (TA98 and TA100) was used for mutagenicity evaluation. Plant different parts were extracted in methanol by shaking, sonication and Soxhlet extraction methods. The R. communis methanolic extracts showed promising antioxidant activity evaluated as through total phenolic contents (TPC), total flavonoid content (TFC), DPPH free radical inhibition, reducing power and inhibition of linoleic acid oxidation. R. communis seeds, stem, leaves, fruit and root methanolic extracts showed mild to moderate cytotoxicity against red blood cells (RBCs) of human and bovine. Brine shrimp lethality also revealed the cytotoxic nature of extracts with LC

Indexed as

AntioxidantBioassaysDNA induced damageExtraction techniquesMedicinal plant

Identifiers

PMID29350299
PMCPMC5775190
OpenAlexW2791014670

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.