Evidence map›Paper›PMID 29350262›Full record

ReviewChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2018

Vagal nerve stimulation for medically refractory epilepsy in Angelman syndrome: a series of three cases.

Krystal L Tomei, Christine Y Mau, Michael Ghali, Jayoung Pak, Ira M Goldstein

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Krystal L TomeiUniversity Hospitals Case Medical Center, Rainbow Babies and Children's Hospital, Cleveland, OH, USA.
Christine Y MauDepartment of Neurological Surgery, Penn State Milton S. Hershey Medical Center, Hershey, PA, USA.
Michael GhaliDepartment of General Surgery, Penn State Milton S. Hershey Medical Center, Hershey, PA, USA.
Jayoung PakDepartment of Neurology, Rutgers New Jersey Medical School Newark, Newark, NJ, USA.
Ira M GoldsteinDepartment of Neurological Surgery, Rutgers New Jersey Medical School, 90 Bergen Street, Suite 8100, Newark, NJ, 07101-1709, USA. goldstir@njms.rutgers.edu.
Penn State Milton S. Hershey Medical Center · USRutgers New Jersey Medical SchoolUniversity Hospitals Case Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe describe three children with Angelman syndrome and medically refractory epilepsy.

methodsCase series of three pediatric patients with Angelman syndrome and medically refractory epilepsy. All three patients failed medical treatment and were recommended for vagal nerve stimulator (VNS) implantation.

resultsFollowing VNS implantation, all three patients experienced reduction in seizure frequency greater than that afforded by medication alone.

conclusionWe present vagal nerve stimulator implantation as a viable treatment option for medically refractory epilepsy associated with Angelman syndrome.

Indexed as

Angelman SyndromeChildChild, PreschoolDrug Resistant EpilepsyFemaleHumansMaleVagus Nerve StimulationAngelman syndromeMedically refractory epilepsyVagal nerve stimulation

Identifiers

PMID29350262
OpenAlexW2784732341

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.