Evidence map›Paper›PMID 29350154›Full record

ArticleEmerging infectious diseases2018

Use of Pristinamycin for Macrolide-Resistant Mycoplasma genitalium Infection.

Tim R H Read, Jørgen S Jensen, Christopher K Fairley, Mieken Grant, Jennifer A Danielewski, Jenny Su, Gerald L Murray, Eric P F Chow, Karen Worthington, Suzanne M Garland and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Emerging infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it, 86 citations in OpenAlex.

  1. German evidence- and consensus-based guideline on the management of penile urethritis.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2025
    Guideline
  2. Review
  3. Antimicrobial resistance crisis in STIs: Gonorrhea andNew microbes and new infections · 2026
    Review
  4. Treatment Approaches for RefractoryOpen forum infectious diseases · 2026
    Article
  5. Article
  6. Novel features ofMicrobial genomics · 2026
    Article
  7. Mycoplasma Genitalium - Where are we at?Current HIV/AIDS reports · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Tropical medicine and infectious disease · 2025
    Article
  13. Antimicrobial agents and chemotherapy · 2025
    Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Canada communicable disease report = Releve des maladies transmissibles au Canada · 2023
    Article
  19. Review
  20. Sexually transmitted infections in Spain: Current status.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Tim R H Read
Jørgen S Jensen
Christopher K Fairley
Mieken Grant
Jennifer A Danielewski
Jenny Su
Gerald L Murray
Eric P F Chow
Karen Worthington
Suzanne M Garland
Sepehr N Tabrizi
Catriona S Bradshaw
Melbourne Sexual Health Centre · AUMurdoch Children's Research Institute · AUAlfred Health · AUStatens Serum Institut · DKMonash University · AURoyal Women's Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High levels of macrolide resistance and increasing fluoroquinolone resistance are found in Mycoplasma genitalium in many countries. We evaluated pristinamycin for macrolide-resistant M. genitalium in a sexual health center in Australia. Microbiologic cure was determined by M. genitalium-specific 16S PCR 14-90 days after treatment began. Of 114 persons treated with pristinamycin, infection was cured in 85 (75%). This percentage did not change when pristinamycin was given at daily doses of 2 g or 4 g or at 3 g combined with 200 mg doxycycline. In infections with higher pretreatment bacterial load, treatment was twice as likely to fail for each 1 log

Indexed as

AdultAnti-Bacterial AgentsDrug Resistance, Multiple, BacterialFemaleHumansMacrolidesMaleMycoplasma genitaliumMycoplasma InfectionsPristinamycinAnti-Bacterial AgentsMacrolidesPristinamycinantimicrobal resistanceAustraliabacteriaMycoplasma genitaliumnongonococcal urethritispelvic inflammatory diseasepristinamycinsexually transmitted infections

Identifiers

PMID29350154
PMCPMC5782881
OpenAlexW2781940573

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.