ArticleEmerging infectious diseases2018
Development of a Pediatric Ebola Predictive Score, Sierra Leone
Article in Emerging infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.
- Clinical and epidemiological performance of WHO Ebola case definitions: a systematic review and meta-analysis.The Lancet. Infectious diseases · 2020Pooled it
- Dynamic modeling of mortality risk factors in Ebola virus disease using logistic regression on unbalanced panel data from a randomized controlled trial in the Democratic Republic of Congo.PLOS global public health · 2025Article
- Rapid Decision Algorithm for Patient Triage during Ebola Outbreaks.Emerging infectious diseases · 2024Article
- Article
- Risk Prediction Score for Pediatric Patients with Suspected Ebola Virus Disease.Emerging infectious diseases · 2022Article
- Development of Ebola virus disease prediction scores: Screening tools for Ebola suspects at the triage-point during an outbreak.PloS one · 2022Article
- Article
- Patient characteristics associated with COVID-19 positivity and fatality in Nigeria: retrospective cohort study.BMJ open · 2020Article
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Authors and funding
21 authors at 8 institutions in 5 countries.
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Abstract
We compared children who were positive for Ebola virus disease (EVD) with those who were negative to derive a pediatric EVD predictor (PEP) score. We collected data on all children <13 years of age admitted to 11 Ebola holding units in Sierra Leone during August 2014-March 2015 and performed multivariable logistic regression. Among 1,054 children, 309 (29%) were EVD positive and 697 (66%) EVD negative, with 48 (5%) missing. Contact history, conjunctivitis, and age were the strongest positive predictors for EVD. The PEP score had an area under receiver operating characteristics curve of 0.80. A PEP score of 7/10 was 92% specific and 44% sensitive; 3/10 was 30% specific, 94% sensitive. The PEP score could correctly classify 79%-90% of children and could be used to facilitate triage into risk categories, depending on the sensitivity or specificity required.
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