ArticleEmerging infectious diseases2018
Increase in Ocular Syphilis Cases at Ophthalmologic Reference Center, France, 2012-2015.
Article in Emerging infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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20 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- Management of Adult Syphilis: Key Questions to Inform the 2021 Centers for Disease Control and Prevention Sexually Transmitted Infections Treatment Guidelines.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022Pooled it
- Risk factors for ocular complications in HIV/AIDS patients: a retrospective analysis of ophthalmology consultations in a tertiary hospital in Central China.BMC ophthalmology · 2026Article
- Case 23: A 26-Year-Old Man Presenting With Right-Eye Visual Disturbances.Journal of Korean medical science · 2026Article
- Syphilitic Uveitis in HIV-Positive and -Negative Patients: A Multicenter Cohort Study.Turkish journal of ophthalmology · 2026Article
- Prevalence of uveitis in syphilis patients in Taiwan.Emerging microbes & infections · 2024Article
- Ocular vs neurosyphilis. are they the same? A guide to investigation and management.Eye (London, England) · 2024Review
- Mimickers of anterior uveitis, scleritis and misdiagnoses- tips and tricks for the cornea specialist.Journal of ophthalmic inflammation and infection · 2024Review
- Pyramidal Inflammatory Deposits of the Retinal Pigment Epithelium and Outer Retina in Ocular Syphilis.Ophthalmology. Retina · 2022Article
- Ocular syphilis resurgence in an urban underserved community in the United States.International journal of ophthalmology · 2022Article
- Demographic, Clinical and Laboratory Characteristics of Ocular Syphilis: 6-Years Case Series Study From an Eye Center in East-China.Frontiers in immunology · 2022Article
- Case report: Visual acuity loss as a warning sign of ocular syphilis: A retrospective analysis of 17 cases.Frontiers in medicine · 2022Article
- Practical Guidance for Clinical Microbiology Laboratories: Diagnosis of Ocular Infections.Clinical microbiology reviews · 2021Review
- Bilateral optic disc swelling resulting from lymphocytic meningitis and posterior uveitis secondary to syphilis.BMJ case reports · 2021Article
- Trends in asymptomatic STI among HIV-positive MSM and lessons for systematic screening.PloS one · 2021Article
- Clinical manifestations and outcomes of ocular syphilis in Asian Indian population: Analysis of cases presenting to a tertiary referral center.Indian journal of ophthalmology · 2020Article
- The importance of proper and prompt treatment of ocular syphilis: a lesson from permanent vision loss in 52 eyes.Journal of the European Academy of Dermatology and Venereology : JEADV · 2020Article
- The Eye as a Window to Systemic Infectious Diseases: Old Enemies, New Imaging.Journal of clinical medicine · 2019Article
- Predictors of unfavorable outcome in neurosyphilis: Multicenter ID-IRI Study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2019Article
- Choroidal neovascularization secondary to ocular syphilis.Romanian journal of ophthalmologyArticle
- Clinical Characteristics of a Case Series of Ocular Syphilis With 3 Cases Requiring Multiple Vitrectomies After Late Diagnosis.Journal of vitreoretinal diseasesArticle
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Authors and funding
17 authors at 2 institutions in 3 countries.
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Abstract
We describe the frequency, demographic and clinical features, and visual outcomes of ocular syphilis infections observed during 2012-2015 at a tertiary reference center in Paris, France. Twenty-one cases (29 eyes) were identified. The occurrence of ocular syphilis increased from 1 case in 2012 to 5 cases in 2013, 6 cases in 2014, and 9 cases in 2015 (2.22-25.21/1,000 individual patients/year for the period). Among case-patients, an annual 20%-33% were co-infected with HIV. Seventy-six percent of ocular syphilis infections occurred in men who have sex with men. Seventy-five percent of case-patients had a good final visual outcome (best-corrected visual acuity >0.3 logMAR score). Visual outcome was worse for HIV-positive patients than for HIV-negative patients (p = 0.0139). At follow-up, the best visual outcomes were observed in patients whose mean time from first ocular symptom to consultation was 15 days (SD +19 days).
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