ArticleEmerging infectious diseases2018
Plasmid-Encoded Transferable mecB-Mediated Methicillin Resistance in Staphylococcus aureus.
Article in Emerging infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 110 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
110 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence of methicillin-resistant coagulase-negative staphylococci in Africa: a systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- Epidemiology of Infections Caused by Gram-Positive Cocci-Microorganisms · 2026Review
- Methicillin-resistant Staphylococcus aureus.Nature reviews. Disease primers · 2026Review
- An Achilles' heel for methicillin-resistantAntimicrobial agents and chemotherapy · 2026Review
- Ecological theory sheds light on plasmid diversity and dynamics.PLoS biology · 2026Article
- Plasmids of co-circulating Staphylococcus aureus serve as vehicles for antimicrobial resistance sharing across diseased host-species at short timescales.BMC microbiology · 2026Article
- Viral community dynamics and functional succession in advanced drinking water treatment processes.Archives of microbiology · 2026Article
- Research Progress onPathogens (Basel, Switzerland) · 2026Review
- Distribution and characteristics of methicillin-resistant staphylococci from non-clinical environments in southern Vietnam.BMC microbiology · 2026Article
- Mammaliicoccus sciuri as a sentinel for antimicrobial resistance and virulence: genomic epidemiology, transmission dynamics, and control in the one health era.Veterinary research communications · 2026Review
- A comprehensive review of emerging therapeutic strategies against methicillin-resistantFrontiers in microbiology · 2026Review
- False positive results obtained with latex agglutination identification of Staphylococcus aureus caused by Macrococcus caseolyticus and Mammaliicoccus fleurettii.Scientific reports · 2025Article
- Environmental spread of mecA-carrying Staphylococcaceae in a Brazilian veterinary teaching hospital: A phenotypic and molecular epidemiological investigation.Veterinary research communications · 2025Article
- Antibacterial Activity of Clove Essential Oil (Pathogens (Basel, Switzerland) · 2025Article
- Prevalence and Characterization ofFoods (Basel, Switzerland) · 2025Article
- Evidence ofApplied and environmental microbiology · 2025Article
- Public health implications of multidrugresistant and methicillinresistant Staphylococcus aureus in retail oysters.Scientific reports · 2025Article
- Emerging Challenges in Methicillin Resistance of Coagulase-Negative Staphylococci.Antibiotics (Basel, Switzerland) · 2025Article
- Prevention and Modern Strategies for Managing Methicillin-Resistant Staphylococcal Infections in Prosthetic Joint Infections (PJIs).Antibiotics (Basel, Switzerland) · 2024Review
- Antimicrobial peptides: A novel and promising arsenal against methicillin-resistantPharmaceutical science advances · 2024Review
50 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
During cefoxitin-based nasal screening, phenotypically categorized methicillin-resistant Staphylococcus aureus (MRSA) was isolated and tested negative for the presence of the mecA and mecC genes as well as for the SCCmec-orfX junction region. The isolate was found to carry a mecB gene previously described for Macrococcus caseolyticus but not for staphylococcal species. The gene is flanked by β-lactam regulatory genes similar to mecR, mecI, and blaZ and is part of an 84.6-kb multidrug-resistance plasmid that harbors genes encoding additional resistances to aminoglycosides (aacA-aphD, aphA, and aadK) as well as macrolides (ermB) and tetracyclines (tetS). This further plasmidborne β-lactam resistance mechanism harbors the putative risk of acceleration or reacceleration of MRSA spread, resulting in broad ineffectiveness of β-lactams as a main therapeutic application against staphylococcal infections.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.