Evidence map›Paper›PMID 29349857›Full record

ArticleAngewandte Chemie (International ed. in English)2018

A Diazido Mannose Analogue as a Chemoenzymatic Synthon for Synthesizing Di-N-acetyllegionaminic Acid-Containing Glycosides.

Abhishek Santra, An Xiao, Hai Yu, Wanqing Li, Yanhong Li, Linh Ngo, John B McArthur, Xi Chen

Open access · greenAbstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Chemoenzymatic Synthesis ofTetrahedron · 2023
    Article
  6. Sialosides Containing 7-ACS infectious diseases · 2023
    Article
  7. Article
  8. Article
  9. Chemoenzymatic Synthesis of Sialosides Containing 7-The Journal of organic chemistry · 2021
    Article
  10. Review
  11. A Chemoenzymatic Synthon Strategy for SynthesizingThe Journal of organic chemistry · 2020
    Article
  12. Article
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Abhishek SantraDepartment of Chemistry, University of California, Davis, One Shields Avenue, Davis, CA, 95616, USA.ORCID 0000-0002-5620-629X
An XiaoDepartment of Chemistry, University of California, Davis, One Shields Avenue, Davis, CA, 95616, USA.ORCID 0000-0002-9726-3039
Hai YuDepartment of Chemistry, University of California, Davis, One Shields Avenue, Davis, CA, 95616, USA.ORCID 0000-0002-4378-0532
Wanqing LiDepartment of Chemistry, University of California, Davis, One Shields Avenue, Davis, CA, 95616, USA.ORCID 0000-0001-6432-5195
Yanhong LiDepartment of Chemistry, University of California, Davis, One Shields Avenue, Davis, CA, 95616, USA.ORCID 0000-0002-6987-6356
Linh NgoDepartment of Chemistry, University of California, Davis, One Shields Avenue, Davis, CA, 95616, USA.ORCID 0000-0003-3268-4323
John B McArthurDepartment of Chemistry, University of California, Davis, One Shields Avenue, Davis, CA, 95616, USA.ORCID 0000-0002-5032-4412
Xi ChenDepartment of Chemistry, University of California, Davis, One Shields Avenue, Davis, CA, 95616, USA.ORCID 0000-0002-3160-614X
University of California, Davis · US

Funding

Chemoenzymatic synthesis of bacterial polysaccharidesU01GM125288 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KIESSLING, LAURA L, LI, LEI · 2017 to 2020
$3.1M
Supplement: Exploring the biology of O-acetyl sialic acids using stable synthetic mimicsR01AI130684 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHEN, XI, VARKI, AJIT P · 2017 to 2020
$2.3M
NIAID NIH HHS R01 AI130684NIGMS NIH HHS U01 GM125288
6 · The paper itself

Abstract

A chemoenzymatic synthon was designed to expand the scope of the chemoenzymatic synthesis of carbohydrates. The synthon was enzymatically converted into carbohydrate analogues, which were readily derivatized chemically to produce the desired targets. The strategy is demonstrated for the synthesis of glycosides containing 7,9-di-N-acetyllegionaminic acid (Leg5,7Ac

Indexed as

AcetylationAzidesBacteriaChemistry Techniques, SyntheticGlycosidesMannoseSialic Acids5,7-diacetamido-8-O-acetyl-3,5,7,9-tetradeoxy-glycero-talo-nonulosonic acidAzidesGlycosidesMannoseSialic Acidscarbohydrateschemoenzymatic synthesisglycosylationlegionaminic acidsialic acid

Identifiers

PMID29349857
PMCPMC5991975
OpenAlexW2789248188

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.