Evidence map›Paper›PMID 29349754›Full record

ReviewCancer treatment and research

Strategies to Maintain Fertility in Young Breast Cancer Patients.

Elizabeth S Constance, Molly B Moravek, Jacqueline S Jeruss

Abstract readReview
PubMed Publisher
In one paragraph

Review in Cancer treatment and research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Elizabeth S ConstanceDepartment of Obstetrics and Gynecology, University of Michigan Health Systems, Ann Arbor, MI, USA.
Molly B MoravekDepartment of Obstetrics and Gynecology, University of Michigan Health Systems, Ann Arbor, MI, USA.
Jacqueline S JerussDepartment of Surgery, University of Michigan, Ann Arbor, MI, USA. jjeruss@med.umich.edu.
University of Michigan–Ann Arbor · USMichigan Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer is the most frequently occurring cancer in women of reproductive age. Treatments for breast cancer may eliminate or diminish fertility, making discussions about fertility preservation essential prior to initiation of gonadotoxic therapies. Additionally, even in patients who do not require chemotherapy, the use of adjuvant endocrine therapy will often push patients out of the reproductive window before treatment is completed. The only established methods for fertility preservation are oocyte or embryo cryopreservation, but experimental methods, such as ovarian suppression with GnRH agonists and ovarian tissue cryopreservation, show great promise. Early referral to a fertility specialist for interested patients affords patients the most fertility preservation options, with only minimal delay to cancer treatment.

Indexed as

Breast NeoplasmsCryopreservationFemaleFertility PreservationHumansOocytesOvulation InductionFertility preservationOncofertilityReproduction

Identifiers

PMID29349754
OpenAlexW2793748876

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.