Evidence map›Paper›PMID 29349599›Full record

ArticleJournal of molecular evolution2018

Evolution of Eukaryal and Archaeal Pseudouridine Synthase Pus10.

Elisabeth Fitzek, Archi Joardar, Ramesh Gupta, Matt Geisler

Open access · greenAbstract read
In one paragraph

Article in Journal of molecular evolution, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

  1. Ψ-Atlas: An Integrated Atlas for Pseudouridine Epitranscriptome.Genomics, proteomics & bioinformatics · 2026
    Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. A dual function PUS enzyme.Nature chemical biology · 2020
    Article
  14. Article
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Elisabeth FitzekDepartment of Plant Biology, Southern Illinois University, Carbondale, IL, 62901-6509, USA.
Archi JoardarDepartment of Biochemistry and Molecular Biology, Southern Illinois University, Carbondale, IL, 62901-4413, USA.
Ramesh GuptaDepartment of Biochemistry and Molecular Biology, Southern Illinois University, Carbondale, IL, 62901-4413, USA.
Matt GeislerDepartment of Plant Biology, Southern Illinois University, Carbondale, IL, 62901-6509, USA. mgeisler@plant.siu.edu.ORCID 0000-0003-1888-4652
Southern Illinois University Carbondale · USNorthern Illinois University · US

Funding

RNA SPLICING IN ARCHAEAR15GM055945 · NIGMS · SOUTHERN ILLINOIS UNIVERSITY CARBONDALE · PI GUPTA, RAMESH · 1998 to 2015
$1.3M
NIGMS NIH HHS R15 GM055945NIH HHS GM55045
6 · The paper itself

Abstract

In archaea, pseudouridine (Ψ) synthase Pus10 modifies uridine (U) to Ψ at positions 54 and 55 of tRNA. In contrast, Pus10 is not found in bacteria, where modifications at those two positions are carried out by TrmA (U54 to m

Indexed as

Amino Acid SequenceAnimalsArchaeaBacteriaBase SequenceBiological EvolutionEscherichia coli ProteinsEukaryotaEvolution, MolecularHumansHydro-LyasesIntramolecular TransferasesPhylogenyPseudogenesRNA, TransfertRNA MethyltransferasesEscherichia coli ProteinsHydro-LyasesIntramolecular Transferasespseudouridine synthasespseudouridylate synthetaseRNA, TransferTrmA protein, E colitRNA MethyltransferasesOrthologsPhylogenyProtein evolutionPseudogeneSubfunctionalization

Identifiers

PMID29349599
PMCPMC5863725
OpenAlexW2786797294

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.