ArticleClinical oral investigations2018
Oral bacterial colonization on dental implants restored with titanium or zirconia abutments: 6-month follow-up.
Article in Clinical oral investigations, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04139538 (Changes of Oral Microbiome and Immunogenity of Saliva During Orthodontic Therapy With Aligners and Multibracket Therapy - a Pilot Study), which is not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Changes of Oral Microbiome and Immunogenity of Saliva During Orthodontic Therapy With Aligners and Multibracket Therapy - a Pilot Study
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- Comparison of Microbiota in Zirconia and Titanium Implants: A Qualitative Systematic Review.International dental journal · 2025Pooled it
- Clinical, Immunological and Microbiological Improvements With Zinc-Coated Healing Abutments During the Healing Phase.International dental journal · 2026Trial
- Surface-related factors affecting bacterial adhesion on dental implants: a short literature review.The journal of advanced prosthodontics · 2026Review
- The shifts of submucosal microbiota in treated patients with aggressive periodontitis.Frontiers in oral health · 2026Article
- Community dynamics during de novo colonization of the nascent peri-implant sulcus.International journal of oral science · 2025Article
- Review
- Effect of implant abutment surface treatments on bacterial biofilm composition and structure.Journal of oral microbiology · 2025Article
- Consensus Report by the Italian Academy of Osseointegration on the Importance of Peri-Implant Soft Tissues.Medicina (Kaunas, Lithuania) · 2024Article
- Bacterial Detection, Deformation, and Torque Loss on Dental Implants with Different Tapered Connections Compared with External Hexagon Connection after Thermomechanical Cycling.Materials (Basel, Switzerland) · 2023Article
- Characterization of the Oral Microbiome in Wearers of Fixed and Removable Implant or Non-Implant-Supported Prostheses in Healthy and Pathological Oral Conditions: A Narrative Review.Microorganisms · 2023Review
- Colonization dynamics of subgingival microbiota in recently installed dental implants compared to healthy teeth in the same individual: a 6-month prospective observational study.Journal of applied oral science : revista FOB · 2023Observational
- Self-ligating brackets exhibit accumulation of high levels of periodontopathogens in gingival crevicular fluid.Odontology · 2022Article
- Succession of oral bacterial colonizers on dental implant materials: An in vitro biofilm model.Dental materials : official publication of the Academy of Dental Materials · 2022Article
- Comparison of oral microbiome profile of polymers modified with silver and vanadium base nanomaterial by next-generation sequencing.Odontology · 2021Article
- Mammalian cell response and bacterial adhesion on titanium healing abutments: effect of multiple implantation and sterilization cycles.Clinical oral investigations · 2021Article
- Bioadhesion in the oral cavity and approaches for biofilm management by surface modifications.Clinical oral investigations · 2020Review
- Article
- Influence of Dental Prosthesis and Restorative Materials Interface on Oral Biofilms.International journal of molecular sciences · 2018Review
- Comparison of initial oral microbiomes of young adults with and without cavitated dentin caries lesions using an in situ biofilm model.Scientific reports · 2018Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveThis investigation aimed to characterize in a 6-month follow-up the microbial profile of implants restored with either titanium or zirconia abutments at the genus or higher taxonomic levels.
methodsTwenty healthy individuals indicative for implant-retained single restorations were investigated. Half of participants were restored with titanium and half with zirconia abutments. Biofilm was collected from the implant-related sites after 1, 3, and 6 months of loading. The 16S rDNA genes were amplified and sequenced with Roche/454 platform.
resultsA total of 596 species were identified in 360 samples and grouped in 18 phyla and 104 genera. Titanium- or zirconia-related sites as well as teeth showed similar total numbers of operational taxonomic units (OTUs) colonizing surfaces over time. Firmicutes, Proteobacteria, Fusobacteria, Bacteroidetes, and Actinobacteria were the most prevalent phyla with significant differences between different surfaces and time point. Unclassified genera were found in lower levels (1.71% up to 9.57%) on titanium and zirconia samples when compared with teeth, with no significant differences.
conclusionTitanium- and zirconia-related surfaces are promptly colonized by a bacterial community similar to those found in the remaining adjacent teeth. Results suggest a selective adhesion of different bacterial genotypes for either titanium or zirconia surfaces. Data also indicate a significant interaction between the relative effects taxa, time point, and sampling site. CLINICAL RELEVANCE: The present study disclosed a wider spectrum of microorganisms colonizing either titanium- or zirconia-related microbiomes in very early stage of implant colonization, revealing differences and suggesting a probably specific mechanism for selective bacterial adhesion.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.