Evidence map›Paper›PMID 29349086›Full record

ArticleBioMed research international2017

Preparation of P3HB4HB/(Gelatin + PVA) Composite Scaffolds by Coaxial Electrospinning and Its Biocompatibility Evaluation.

Min-Xian Ma, Qin Liu, Chuan Ye, Brian Grottkau, Bing Guo, Yu-Feng Song

Abstract read
In one paragraph

Article in BioMed research international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Min-Xian MaGuizhou Medical University, Guiyang 550004, China.
Qin LiuGuizhou Medical University, Guiyang 550004, China.
Chuan YeDepartment of Orthopaedics, The Affiliated Hospital of Guizhou Medical University, Guiyang 550004, China.ORCID 0000-0001-5670-6289
Brian GrottkauDepartment of Orthopaedics, Massachusetts General Hospital, Boston, MA 02115, USA.
Bing GuoGuizhou Medical University, Guiyang 550004, China.
Yu-Feng SongGuizhou Medical University, Guiyang 550004, China.ORCID 0000-0001-6200-067X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study was conducted to prepare coaxial electrospun scaffolds of P3HB4HB/(gelatin + PVA) with various concentration ratios with P3HB4HB as the core solution and gelatin + PVA mixture as the shell solution; the mass ratios of gelatin and PVA in each 10 mL shell mixture were 0.6 g : 0.2 g (Group A), 0.4 g : 0.4 g (Group B), and 0.2 g : 0.6 g (Group C). The results showed that the pore size, porosity, and cell proliferation rate of Group C were better than those of Groups A and B. The ascending order of the tensile strength and modulus of elasticity was Group A < Group B < Group C. The surface roughness was Group C > Group B > Group A. The osteogenic and chondrogenic-specific staining showed that Group C was stronger than Groups A and B. This study demonstrates that when the mass ratio of gelatin : PVA was 0.2 g : 0.6 g, a P3HB4HB/(gelatin + PVA) composite scaffold with a core-shell structure can be prepared, and the scaffold has good biocompatibility that it may be an ideal scaffold for tissue engineering.

Indexed as

Biocompatible MaterialsCell AdhesionCell ProliferationCells, CulturedGelatinHumansMaterials TestingMesenchymal Stem CellsPolyvinyl AlcoholPorositySurface PropertiesTissue EngineeringTissue ScaffoldsBiocompatible MaterialsGelatinPolyvinyl Alcohol

Identifiers

PMID29349086
PMCPMC5733976

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.