Evidence map›Paper›PMID 29349082›Full record

ArticleBioMed research international2017

Efficacy of One-Year Treatment with Aflibercept for Diabetic Macular Edema with Practical Protocol.

Tomomi Kaiho, Toshiyuki Oshitari, Tomoaki Tatsumi, Yoko Takatsuna, Miyuki Arai, Norihiro Shimizu, Eiju Sato, Takayuki Baba, Shuichi Yamamoto

Abstract read
In one paragraph

Article in BioMed research international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Neurovascular Impairment and Therapeutic Strategies in Diabetic Retinopathy.International journal of environmental research and public health · 2021
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tomomi KaihoDepartment of Ophthalmology and Visual Science, Chiba University, Graduate School of Medicine, Chiba, Japan.
Toshiyuki OshitariDepartment of Ophthalmology and Visual Science, Chiba University, Graduate School of Medicine, Chiba, Japan.ORCID 0000-0002-8273-845X
Tomoaki TatsumiDepartment of Ophthalmology and Visual Science, Chiba University, Graduate School of Medicine, Chiba, Japan.
Yoko TakatsunaDepartment of Ophthalmology and Visual Science, Chiba University, Graduate School of Medicine, Chiba, Japan.
Miyuki AraiDepartment of Ophthalmology and Visual Science, Chiba University, Graduate School of Medicine, Chiba, Japan.
Norihiro ShimizuDepartment of Ophthalmology and Visual Science, Chiba University, Graduate School of Medicine, Chiba, Japan.
Eiju SatoDepartment of Ophthalmology and Visual Science, Chiba University, Graduate School of Medicine, Chiba, Japan.
Takayuki BabaDepartment of Ophthalmology and Visual Science, Chiba University, Graduate School of Medicine, Chiba, Japan.ORCID 0000-0002-8178-8391
Shuichi YamamotoDepartment of Ophthalmology and Visual Science, Chiba University, Graduate School of Medicine, Chiba, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study was to determine the efficacy of one-year treatment of diabetic macular edema (DME) with intravitreal aflibercept (IVA) injections on a practical protocol. The medical records of 51 eyes of 43 patients who were diagnosed with DME and had received IVA treatments were reviewed. The best-corrected visual acuity (BCVA) and the central macular thickness (CMT) were measured at the baseline and at 1, 3, 6, and 12 months after the IVA. The mean number of IVA injections was 3.8 ± 2.4. The mean BCVA was significantly better and the CMT was thinner after the IVA at all follow-up times (

Indexed as

AgedAngiogenesis InhibitorsDiabetic RetinopathyFemaleHumansIntravitreal InjectionsMacular EdemaMaleMiddle AgedReceptors, Vascular Endothelial Growth FactorRecombinant Fusion ProteinsRetinal Pigment EpitheliumRetrospective StudiesVisual AcuityafliberceptAngiogenesis InhibitorsReceptors, Vascular Endothelial Growth FactorRecombinant Fusion Proteins

Identifiers

PMID29349082
PMCPMC5733831

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.