ArticleBioMed research international2017
Modulation of Immune Function in Rats Using Oligosaccharides Extracted from Palm Kernel Cake.
Article in BioMed research international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 15 citations in OpenAlex.
- Palm kernel cake and decanter cake as broiler feed ingredients: Effects on immunity, gut microbiota, antioxidant gene expression and plasma lipid profile.Poultry science · 2026Article
- Comprehensive utilization of palm kernel cake for producing mannose and manno-oligosaccharide mixture and yeast culture.Applied microbiology and biotechnology · 2022Article
- Upgrading the Nutritional Value of PKC Using aMolecules (Basel, Switzerland) · 2022Article
- Ameliorative Effects ofAntioxidants (Basel, Switzerland) · 2021Article
- Is Palm Kernel Cake a Suitable Alternative Feed Ingredient for Poultry?Animals : an open access journal from MDPI · 2021Review
- Oligosaccharides from Palm Kernel Cake Enhances Adherence Inhibition and Intracellular Clearance ofMicroorganisms · 2020Article
- Palm Kernel Cake Oligosaccharides Acute Toxicity and Effects on Nitric Oxide Levels Using a Zebrafish Larvae Model.Frontiers in physiology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To investigate the prebiotic and immunomodulatory effects of PKC extract (OligoPKC) a total of 24 male rats were randomly assigned to three treatment groups receiving basal diet (control), basal diet containing 0.5% OligoPKC, or basal diet containing 1% OligoPKC for four weeks. We found that OligoPKC had no significant effect on the tested growth parameters. However, it increased the size of the total and beneficial bacterial populations while reducing pathogen populations. OligoPKC increased the concentration of immunoglobulins in the serum and cecal contents of rats. It also enhanced the antioxidant capacity of the liver while reducing lipid peroxidation in liver tissue. OligoPKC affected the expression of genes involved in immune system function in the intestine. Therefore, OligoPKC could be considered a potential mannan-based prebiotic for humans and animals due to its beneficial effects on the health and well-being of the model rats.
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Registered trials
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