ArticlePain research & management2017
Disentangling the Sleep-Pain Relationship in Pediatric Chronic Pain: The Mediating Role of Internalizing Mental Health Symptoms.
Article in Pain research & management, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.
- Measuring mental wellness among adolescents living with a physical chronic condition: a systematic review of the mental health and mental well-being instruments.BMC psychology · 2021Pooled it
- Sleep and Pain: A Systematic Review of Studies of Mediation.The Clinical journal of pain · 2019Pooled it
- "Hurt and Misunderstood": Emotional reactions to pain dismissal in emerging adults with chronic pain.Health care transitions · 2025Article
- Changes in sleep patterns in primary care workers during the first wave of the COVID-19 pandemic in 2022 in Shanghai: a cross-sectional study.Scientific reports · 2024Article
- Exploring Referral and Service Utilization Patterns Within an Outpatient Interdisciplinary Pediatric Chronic Pain Program.Journal of pain research · 2024Article
- Healthcare Professionals' Knowledge about Pediatric Chronic Pain: A Systematic Review.Children (Basel, Switzerland) · 2023Review
- The complexities of the sleep-pain relationship in adolescents: A critical review.Sleep medicine reviews · 2023Review
- Prevention is better than cure: why early interventions for insomnia and chronic pain during adolescence should be a priority.Frontiers in psychology · 2023Article
- Pain, depressive symptoms, and health-related quality of life among survivors of pediatric hematopoietic stem cell transplant.Pediatric blood & cancer · 2022Article
- Pediatric sleep and pain: etiologies, consequences, and clinical considerations.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Review
- A mediating role for mental health in associations between COVID-19-related self-stigma, PTSD, quality of life, and insomnia among patients recovered from COVID-19.Brain and behavior · 2021Article
- Article
- The Role of Sleep in the Transition from Acute to Chronic Musculoskeletal Pain in Youth-A Narrative Review.Children (Basel, Switzerland) · 2021Review
- Autistic Traits and Attention-Deficit Hyperactivity Disorder Symptoms Associated With Greater Pain Interference and Depression, and Reduced Health-Related Quality of Life in Children With Chronic Pain.Frontiers in neuroscience · 2021Article
- The Pittsburgh Sleep Quality Index: Reliability, Factor Structure, and Related Clinical Factors among Children, Adolescents, and Young Adults with Chronic Pain.Sleep disorders · 2021Article
- Effect of pain on mood affective disorders in adults with cerebral palsy.Developmental medicine and child neurology · 2020Article
- Clinical factors associated with mood affective disorders among adults with cerebral palsy.Neurology. Clinical practice · 2020Article
- The role of sleep quality on the relationship between posttraumatic stress symptoms and pain in women.Journal of behavioral medicine · 2019Article
- Evaluation of clinical outcomes in an interdisciplinary abdominal pain clinic: A retrospective, exploratory review.World journal of gastroenterology · 2019Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Pediatric chronic pain often emerges in adolescence and cooccurs with internalizing mental health issues and sleep impairments. Emerging evidence suggests that sleep problems may precede the onset of chronic pain as well as anxiety and depression. Studies conducted in pediatric populations with pain-related chronic illnesses suggest that internalizing mental health symptoms may mediate the sleep-pain relationship; however, this has not been examined in youth with primary pain disorders. Objective: To examine whether anxiety and depressive symptoms mediated relationships between sleep quality and pain outcomes among youth with chronic pain. Methods: Participants included 147 youth (66.7% female) aged 8-18 years who were referred to a tertiary-level chronic pain program. At intake, the youth completed psychometrically sound measures of sleep quality, pain intensity, pain interference, and anxiety and depressive symptoms. Results: As hypothesized, poor sleep quality was associated with increased pain intensity and pain interference, and anxiety and depressive symptoms mediated these sleep-pain relationships. Discussion: For youth with chronic pain, poor sleep quality may worsen pain through alterations in mood and anxiety; however, prospective research using objective measures is needed. Future research should examine whether targeting sleep and internalizing mental health symptoms in treatments improve pain outcomes in these youth.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.